Evaluation of the Endothelin Receptor Antagonists Ambrisentan, Bosentan, Macitentan, and Sitaxsentan as Hepatobiliary Transporter Inhibitors and Substrates in Sandwich-Cultured Human Hepatocytes

• Eve-Irene Lepist,

  Affiliation Gilead Sciences, Inc., Foster City, California, United States of America

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• Hunter Gillies,

  Affiliation Gilead Sciences, Inc., Foster City, California, United States of America

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• William Smith,

  Affiliation Qualyst Transporter Solutions, LLC, Durham, North Carolina, United States of America

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• Jia Hao,

  Affiliation Gilead Sciences, Inc., Foster City, California, United States of America

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• Cassandra Hubert,

  Affiliation Qualyst Transporter Solutions, LLC, Durham, North Carolina, United States of America

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• Robert L. St. Claire III,

  Affiliation Qualyst Transporter Solutions, LLC, Durham, North Carolina, United States of America

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• Kenneth R. Brouwer,

  Affiliation Qualyst Transporter Solutions, LLC, Durham, North Carolina, United States of America

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• Adrian S. Ray

  * E-mail: Adrian.Ray@gilead.com

  Affiliation Gilead Sciences, Inc., Foster City, California, United States of America

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