Associations of MTHFR Gene Polymorphisms with Hypertension and Hypertension in Pregnancy: A Meta-Analysis from 114 Studies with 15411 Cases and 21970 Controls

Boyi Yang; Shujun Fan; Xueyuan Zhi; Yongfang Li; Yuyan Liu; Da Wang; Miao He; Yongyong Hou; Quanmei Zheng; Guifan Sun

doi:10.1371/journal.pone.0087497

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Peer-reviewed

Research Article

Associations of MTHFR Gene Polymorphisms with Hypertension and Hypertension in Pregnancy: A Meta-Analysis from 114 Studies with 15411 Cases and 21970 Controls

Boyi Yang,

Affiliation Environment and Non-Communicable Diseases Research Center, School of Public Health, China Medical University, Shenyang, China
⨯
Shujun Fan,

Affiliation Environment and Non-Communicable Diseases Research Center, School of Public Health, China Medical University, Shenyang, China
⨯
Xueyuan Zhi,

Affiliation Environment and Non-Communicable Diseases Research Center, School of Public Health, China Medical University, Shenyang, China
⨯
Yongfang Li,

Affiliation Environment and Non-Communicable Diseases Research Center, School of Public Health, China Medical University, Shenyang, China
⨯
Yuyan Liu,

Affiliation Environment and Non-Communicable Diseases Research Center, School of Public Health, China Medical University, Shenyang, China
⨯
Da Wang,

Affiliation Environment and Non-Communicable Diseases Research Center, School of Public Health, China Medical University, Shenyang, China
⨯
Miao He,

Affiliation Environment and Non-Communicable Diseases Research Center, School of Public Health, China Medical University, Shenyang, China
⨯
Yongyong Hou,

Affiliation Department of Medical and Molecular Genetics, School of Medicine, Indiana University, Indianapolis, Indiana, United States of America
⨯
Quanmei Zheng,

Affiliation Environment and Non-Communicable Diseases Research Center, School of Public Health, China Medical University, Shenyang, China
⨯
Guifan Sun

* E-mail: sungf@mail.cmu.edu.cn

Affiliation Environment and Non-Communicable Diseases Research Center, School of Public Health, China Medical University, Shenyang, China
⨯

Associations of MTHFR Gene Polymorphisms with Hypertension and Hypertension in Pregnancy: A Meta-Analysis from 114 Studies with 15411 Cases and 21970 Controls

Boyi Yang,
Shujun Fan,
Xueyuan Zhi,
Yongfang Li,
Yuyan Liu,
Da Wang,
Miao He,
Yongyong Hou,
Quanmei Zheng,
Guifan Sun

Published: February 5, 2014
https://doi.org/10.1371/journal.pone.0087497

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