Humanized HLA-DR4 Mice Fed with the Protozoan Pathogen of Oysters Perkinsus Marinus (Dermo) Do Not Develop Noticeable Pathology but Elicit Systemic Immunity

Wathsala Wijayalath; Sai Majji; Yuliya Kleschenko; Luis Pow-Sang; Teodor D. Brumeanu; Eileen Franke Villasante; Gerardo R. Vasta; José-Antonio Fernández-Robledo; Sofia Casares

doi:10.1371/journal.pone.0087435

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Research Article

Humanized HLA-DR4 Mice Fed with the Protozoan Pathogen of Oysters Perkinsus Marinus (Dermo) Do Not Develop Noticeable Pathology but Elicit Systemic Immunity

Wathsala Wijayalath ,

Contributed equally to this work with: Wathsala Wijayalath, Sai Majji

Affiliation US Military Malaria Vaccine Program, Naval Medical Research Center/Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America
⨯
Sai Majji ,

Contributed equally to this work with: Wathsala Wijayalath, Sai Majji

Affiliation US Military Malaria Vaccine Program, Naval Medical Research Center/Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America
⨯
Yuliya Kleschenko,

Affiliation US Military Malaria Vaccine Program, Naval Medical Research Center/Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America
⨯
Luis Pow-Sang,

Affiliation Department of Medicine, Uniformed Services University of Health Sciences, Bethesda, Maryland, United States of America
⨯
Teodor D. Brumeanu,

Affiliation Department of Medicine, Uniformed Services University of Health Sciences, Bethesda, Maryland, United States of America
⨯
Eileen Franke Villasante,

Affiliation US Military Malaria Vaccine Program, Naval Medical Research Center/Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America
⨯
Gerardo R. Vasta,

Affiliation Department of Microbiology and Immunology, University of Maryland Baltimore School of Medicine, Baltimore, Maryland, United States of America
⨯
José-Antonio Fernández-Robledo,

Current address: Bigelow Laboratory for Ocean Sciences, East Boothbay, Maine, United States of America

Affiliation Department of Microbiology and Immunology, University of Maryland Baltimore School of Medicine, Baltimore, Maryland, United States of America
⨯
Sofia Casares

* E-mail: sofia.casares@med.navy.mil

Affiliations US Military Malaria Vaccine Program, Naval Medical Research Center/Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America, Department of Medicine, Uniformed Services University of Health Sciences, Bethesda, Maryland, United States of America
⨯

Humanized HLA-DR4 Mice Fed with the Protozoan Pathogen of Oysters Perkinsus Marinus (Dermo) Do Not Develop Noticeable Pathology but Elicit Systemic Immunity

Wathsala Wijayalath,
Sai Majji,
Yuliya Kleschenko,
Luis Pow-Sang,
Teodor D. Brumeanu,
Eileen Franke Villasante,
Gerardo R. Vasta,
José-Antonio Fernández-Robledo,
Sofia Casares

Published: January 31, 2014
https://doi.org/10.1371/journal.pone.0087435

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