Introduction of Mismatches in a Random shRNA-Encoding Library Improves Potency for Phenotypic Selection

Open Access

Peer-reviewed

Research Article

Yongping Wang,

Affiliations Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States of America, Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America
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Jacqueline S. Speier,

Affiliation Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America
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Jessica Engram-Pearl,

Affiliation Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
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Robert B. Wilson

* E-mail: wilsonr@mail.med.upenn.edu

Affiliation Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
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Library screening
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Small interfering RNA
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RNA interference
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MicroRNAs
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cDNA libraries
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Genomics
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