Neurological and Histological Consequences Induced by In Vivo Cerebral Oxidative Stress: Evidence for Beneficial Effects of SRT1720, a Sirtuin 1 Activator, and Sirtuin 1-Mediated Neuroprotective Effects of Poly(ADP-ribose) Polymerase Inhibition

Open Access

Peer-reviewed

Research Article

Cindy Gueguen,

Affiliation Université Paris Descartes, Pharmacologie de la Circulation Cérébrale - EA4475, Faculté des Sciences Pharmaceutiques et Biologiques, Paris, France
⨯
Bruno Palmier,

Affiliation Université Paris Descartes, Pharmacologie de la Circulation Cérébrale - EA4475, Faculté des Sciences Pharmaceutiques et Biologiques, Paris, France
⨯
Michel Plotkine,

Affiliation Université Paris Descartes, Pharmacologie de la Circulation Cérébrale - EA4475, Faculté des Sciences Pharmaceutiques et Biologiques, Paris, France
⨯
Catherine Marchand-Leroux,

Affiliation Université Paris Descartes, Pharmacologie de la Circulation Cérébrale - EA4475, Faculté des Sciences Pharmaceutiques et Biologiques, Paris, France
⨯
Valérie C. Besson

* E-mail: valerie.besson@parisdescartes.fr

Affiliation Université Paris Descartes, Pharmacologie de la Circulation Cérébrale - EA4475, Faculté des Sciences Pharmaceutiques et Biologiques, Paris, France
⨯

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Oxidative stress
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Malonates
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Neuroprotectives
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Cell death
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Histology
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Neostriatum
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Neuronal death
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Stroke
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