BMI-Associated Alleles Do Not Constitute Risk Alleles for Polycystic Ovary Syndrome Independently of BMI: A Case-Control Study

Yvonne V. Louwers; Nigel W. Rayner; Blanca M. Herrera; Lisette Stolk; Christopher J. Groves; Thomas M. Barber; Andre G. Uitterlinden; Stephen Franks; Joop S. E. Laven; Mark I. McCarthy

doi:10.1371/journal.pone.0087335

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Peer-reviewed

Research Article

BMI-Associated Alleles Do Not Constitute Risk Alleles for Polycystic Ovary Syndrome Independently of BMI: A Case-Control Study

Yvonne V. Louwers,

Affiliation Department of Obstetrics and Gynecology, Subdivision of Reproductive Medicine, Erasmus MC University Medical Center, Rotterdam, the Netherlands
⨯
Nigel W. Rayner,

Affiliations Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom, Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, United Kingdom
⨯
Blanca M. Herrera,

Affiliation Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom
⨯
Lisette Stolk,

Affiliation Department of Internal Medicine, Erasmus MC University Medical Center, Rotterdam, the Netherlands
⨯
Christopher J. Groves,

Affiliations Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom, Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, United Kingdom
⨯
Thomas M. Barber,

Affiliation Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, United Kingdom
⨯
Andre G. Uitterlinden,

Affiliations Department of Internal Medicine, Erasmus MC University Medical Center, Rotterdam, the Netherlands, Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, the Netherlands
⨯
Stephen Franks,

Affiliation Institute of Reproductive and Developmental Biology, Imperial College London, Hammersmith Hospital, London, United Kingdom
⨯
Joop S. E. Laven ,

Contributed equally to this work with: Joop S. E. Laven, Mark I. McCarthy

* E-mail: mark.mccarthy@drl.ox.ac.uk (MIM); j.laven@erasmusmc.nl (JSEL)

Affiliation Department of Obstetrics and Gynecology, Subdivision of Reproductive Medicine, Erasmus MC University Medical Center, Rotterdam, the Netherlands
⨯
Mark I. McCarthy

Contributed equally to this work with: Joop S. E. Laven, Mark I. McCarthy

* E-mail: mark.mccarthy@drl.ox.ac.uk (MIM); j.laven@erasmusmc.nl (JSEL)

Affiliations Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom, Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, United Kingdom
⨯

BMI-Associated Alleles Do Not Constitute Risk Alleles for Polycystic Ovary Syndrome Independently of BMI: A Case-Control Study

Yvonne V. Louwers,
Nigel W. Rayner,
Blanca M. Herrera,
Lisette Stolk,
Christopher J. Groves,
Thomas M. Barber,
Andre G. Uitterlinden,
Stephen Franks,
Joop S. E. Laven,
Mark I. McCarthy

Published: January 31, 2014
https://doi.org/10.1371/journal.pone.0087335

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Body mass index
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Single nucleotide polymorphisms
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