Chemical Rescue and Inhibition Studies to Determine the Role of Arg301 in Phosphite Dehydrogenase

Open Access

Peer-reviewed

Research Article

John E. Hung,

Affiliation Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America
⨯
Emily J. Fogle,

Affiliation Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America
⨯
Neha Garg,

Affiliation Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America
⨯
Jonathan R. Chekan,

Affiliation Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America
⨯
Satish K. Nair,

Affiliations Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America, Center for Biophysics and Computational Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America
⨯
Wilfred A. van der Donk

* E-mail: vddonk@illinois.edu

Affiliations Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America, Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America, Howard Hughes Medical Institute, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America
⨯

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Crystal structure
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Catalysis
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Guanidines
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Transition state
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Hydrides
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