Tumor Vasculature-Targeted Recombinant Mutated Human TNF-α Enhanced the Antitumor Activity of Doxorubicin by Increasing Tumor Vessel Permeability in Mouse Xenograft Models

• Changli Jiang ,

  Contributed equally to this work with: Changli Jiang, Junzhou Niu

  Affiliations Clinical Laboratory, Army Center for Molecular Biological Analysis, Kunming General Hospital of Chengdu Military Area, Kunming, Yunnna, China, The State Key Laboratory of Cancer Biology, Department of Biopharmaceutics, School of Pharmacy, Fourth Military Medical University, Xi’an, Shaanxi, China

  ⨯
• Junzhou Niu ,

  Contributed equally to this work with: Changli Jiang, Junzhou Niu

  Affiliation Department of Dermatology, Xijing Hospital, Fourth Military Medical University, Xi’an, Shaanxi, China

  ⨯
• Meng Li,

  Affiliation The State Key Laboratory of Cancer Biology, Department of Biopharmaceutics, School of Pharmacy, Fourth Military Medical University, Xi’an, Shaanxi, China

  ⨯
• Yi Teng,

  Affiliation Clinical Laboratory, Army Center for Molecular Biological Analysis, Kunming General Hospital of Chengdu Military Area, Kunming, Yunnna, China

  ⨯
• Huixuan Wang ,

  * E-mail: dywang43@163.com (HW); zhangyqh@fmmu.edu.cn (YZ)

  Affiliation Clinical Laboratory, Army Center for Molecular Biological Analysis, Kunming General Hospital of Chengdu Military Area, Kunming, Yunnna, China

  ⨯
• Yingqi Zhang

  * E-mail: dywang43@163.com (HW); zhangyqh@fmmu.edu.cn (YZ)

  Affiliation The State Key Laboratory of Cancer Biology, Department of Biopharmaceutics, School of Pharmacy, Fourth Military Medical University, Xi’an, Shaanxi, China

  ⨯