Evaluation of Hyperpolarized [1-13C]-Pyruvate by Magnetic Resonance to Detect Ionizing Radiation Effects in Real Time

Vlad C. Sandulache; Yunyun Chen; Jaehyuk Lee; Ashley Rubinstein; Marc S. Ramirez; Heath D. Skinner; Christopher M. Walker; Michelle D. Williams; Ramesh Tailor; Laurence E. Court; James A. Bankson; Stephen Y. Lai

doi:10.1371/journal.pone.0087031

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Open Access

Peer-reviewed

Research Article

Evaluation of Hyperpolarized [1-¹³C]-Pyruvate by Magnetic Resonance to Detect Ionizing Radiation Effects in Real Time

Vlad C. Sandulache,

Affiliations Bobby R. Alford Department of Otolaryngology, Head and Neck Surgery, Baylor College of Medicine, Houston, Texas, United States of America, Department of Head and Neck Surgery, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America
⨯
Yunyun Chen,

Affiliation Department of Head and Neck Surgery, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America
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Jaehyuk Lee,

Affiliation Department of Imaging Physics, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America
⨯
Ashley Rubinstein,

Affiliation Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
⨯
Marc S. Ramirez,

Affiliation Department of Imaging Physics, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America
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Heath D. Skinner,

Affiliation Department of Radiation Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America
⨯
Christopher M. Walker,

Affiliation Department of Imaging Physics, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America
⨯
Michelle D. Williams,

Affiliation Department of Pathology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States of America
⨯
Ramesh Tailor,

Affiliation Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
⨯
Laurence E. Court,

Affiliation Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
⨯
James A. Bankson,

Affiliation Department of Imaging Physics, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America
⨯
Stephen Y. Lai

* E-mail: SYLai@mdanderson.org

Affiliations Department of Head and Neck Surgery, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America, Department of Molecular and Cellular Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States of America
⨯

Evaluation of Hyperpolarized [1-¹³C]-Pyruvate by Magnetic Resonance to Detect Ionizing Radiation Effects in Real Time

Vlad C. Sandulache,
Yunyun Chen,
Jaehyuk Lee,
Ashley Rubinstein,
Marc S. Ramirez,
Heath D. Skinner,
Christopher M. Walker,
Michelle D. Williams,
Ramesh Tailor,
Laurence E. Court

Published: January 27, 2014
https://doi.org/10.1371/journal.pone.0087031

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