Molecular Analysis of Serum and Bronchoalveolar Lavage in a Mouse Model of Influenza Reveals Markers of Disease Severity That Can Be Clinically Useful in Humans

Yadunanda Kumar; Cui Liang; Gino V. Limmon; Li Liang; Bevin P. Engelward; Eng Eong Ooi; Jianzhu Chen; Steven R. Tannenbaum

doi:10.1371/journal.pone.0086912

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Open Access

Peer-reviewed

Research Article

Molecular Analysis of Serum and Bronchoalveolar Lavage in a Mouse Model of Influenza Reveals Markers of Disease Severity That Can Be Clinically Useful in Humans

Yadunanda Kumar ,

* E-mail: ybudigi@mit.edu

Affiliations Interdisciplinary research group in Infectious disease, Singapore-MIT Alliance for research and technology (SMART), Singapore, Singapore, Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
⨯
Cui Liang,

Affiliation Interdisciplinary research group in Infectious disease, Singapore-MIT Alliance for research and technology (SMART), Singapore, Singapore
⨯
Gino V. Limmon,

Affiliation Interdisciplinary research group in Infectious disease, Singapore-MIT Alliance for research and technology (SMART), Singapore, Singapore
⨯
Li Liang,

Affiliation Interdisciplinary research group in Infectious disease, Singapore-MIT Alliance for research and technology (SMART), Singapore, Singapore
⨯
Bevin P. Engelward,

Affiliations Interdisciplinary research group in Infectious disease, Singapore-MIT Alliance for research and technology (SMART), Singapore, Singapore, Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
⨯
Eng Eong Ooi,

Affiliations Interdisciplinary research group in Infectious disease, Singapore-MIT Alliance for research and technology (SMART), Singapore, Singapore, DUKE-NUS Graduate Medical School, Singapore, Singapore
⨯
Jianzhu Chen,

Affiliations Interdisciplinary research group in Infectious disease, Singapore-MIT Alliance for research and technology (SMART), Singapore, Singapore, Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
⨯
Steven R. Tannenbaum

Affiliations Interdisciplinary research group in Infectious disease, Singapore-MIT Alliance for research and technology (SMART), Singapore, Singapore, Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
⨯

Molecular Analysis of Serum and Bronchoalveolar Lavage in a Mouse Model of Influenza Reveals Markers of Disease Severity That Can Be Clinically Useful in Humans

Yadunanda Kumar,
Cui Liang,
Gino V. Limmon,
Li Liang,
Bevin P. Engelward,
Eng Eong Ooi,
Jianzhu Chen,
Steven R. Tannenbaum

Published: February 5, 2014
https://doi.org/10.1371/journal.pone.0086912

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