Hsp90 Binds Directly to Fibronectin (FN) and Inhibition Reduces the Extracellular Fibronectin Matrix in Breast Cancer Cells

Open Access

Peer-reviewed

Research Article

Morgan C. Hunter ,

Contributed equally to this work with: Morgan C. Hunter, Kyle L. O’Hagan

Affiliation Biomedical Biotechnology Research Unit, Department of Biochemistry, Microbiology and Biotechnology, Rhodes University, Grahamstown, Eastern Cape, South Africa
⨯
Kyle L. O’Hagan ,

Contributed equally to this work with: Morgan C. Hunter, Kyle L. O’Hagan

Affiliation Biomedical Biotechnology Research Unit, Department of Biochemistry, Microbiology and Biotechnology, Rhodes University, Grahamstown, Eastern Cape, South Africa
⨯
Amy Kenyon,

Affiliation Biomedical Biotechnology Research Unit, Department of Biochemistry, Microbiology and Biotechnology, Rhodes University, Grahamstown, Eastern Cape, South Africa
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Karim C. H. Dhanani,

Affiliation Biomedical Biotechnology Research Unit, Department of Biochemistry, Microbiology and Biotechnology, Rhodes University, Grahamstown, Eastern Cape, South Africa
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Earl Prinsloo,

Affiliation Biomedical Biotechnology Research Unit, Department of Biochemistry, Microbiology and Biotechnology, Rhodes University, Grahamstown, Eastern Cape, South Africa
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Adrienne L. Edkins

* E-mail: a.edkins@ru.ac.za

Affiliation Biomedical Biotechnology Research Unit, Department of Biochemistry, Microbiology and Biotechnology, Rhodes University, Grahamstown, Eastern Cape, South Africa
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Extracellular matrix
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Immunoblotting
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Immunoprecipitation
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Confocal microscopy
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Extracellular matrix proteins
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Breast cancer
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Cell staining
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Small interfering RNA
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