Cyclophosphamide Alters the Gene Expression Profile in Patients Treated with High Doses Prior to Stem Cell Transplantation

Ibrahim El-Serafi; Manuchehr Abedi-Valugerdi; Zuzana Potácová; Parvaneh Afsharian; Jonas Mattsson; Ali Moshfegh; Moustapha Hassan

doi:10.1371/journal.pone.0086619

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Peer-reviewed

Research Article

Cyclophosphamide Alters the Gene Expression Profile in Patients Treated with High Doses Prior to Stem Cell Transplantation

Ibrahim El-Serafi,

Affiliation Experimental Cancer Medicine (ECM), Clinical Research Centre (KFC), Department of Laboratory Medicine, Karolinska Institutet, Huddinge, Stockholm, Sweden
⨯
Manuchehr Abedi-Valugerdi,

Affiliation Experimental Cancer Medicine (ECM), Clinical Research Centre (KFC), Department of Laboratory Medicine, Karolinska Institutet, Huddinge, Stockholm, Sweden
⨯
Zuzana Potácová,

Affiliations Experimental Cancer Medicine (ECM), Clinical Research Centre (KFC), Department of Laboratory Medicine, Karolinska Institutet, Huddinge, Stockholm, Sweden, Clinical Research Centre (Novum), Karolinska University Hospital-Huddinge, Stockholm, Sweden
⨯
Parvaneh Afsharian,

Affiliations Experimental Cancer Medicine (ECM), Clinical Research Centre (KFC), Department of Laboratory Medicine, Karolinska Institutet, Huddinge, Stockholm, Sweden, Department of Genetics, Royan Institute, Tehran, Iran
⨯
Jonas Mattsson,

Affiliations Centre for Allogeneic Stem Cell Transplantation, Karolinska University Hospital-Huddinge, Stockholm, Sweden, Department of Therapeutic Immunology, Karolinska Institute, Karolinska University Hospital, Huddinge, Stockholm, Sweden
⨯
Ali Moshfegh,

Affiliation Cancer Centre of Karolinska (CCK), Department of Oncology-Pathology, Karolinska Institutet, Solna, Stockholm, Sweden
⨯
Moustapha Hassan

* E-mail: moustapha.hassan@ki.se

Affiliations Experimental Cancer Medicine (ECM), Clinical Research Centre (KFC), Department of Laboratory Medicine, Karolinska Institutet, Huddinge, Stockholm, Sweden, Clinical Research Centre (Novum), Karolinska University Hospital-Huddinge, Stockholm, Sweden
⨯

Cyclophosphamide Alters the Gene Expression Profile in Patients Treated with High Doses Prior to Stem Cell Transplantation

Ibrahim El-Serafi,
Manuchehr Abedi-Valugerdi,
Zuzana Potácová,
Parvaneh Afsharian,
Jonas Mattsson,
Ali Moshfegh,
Moustapha Hassan

Published: January 22, 2014
https://doi.org/10.1371/journal.pone.0086619

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Cancer treatment
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Gene expression
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T cells
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Cyclophosphamide
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MAPK signaling cascades
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Stem cell therapy
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Hematopoietic stem cell transplantation
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