Arsenic Trioxide Induces Apoptosis in Human Platelets via C-Jun NH2-Terminal Kinase Activation

Open Access

Peer-reviewed

Research Article

Arsenic Trioxide Induces Apoptosis in Human Platelets via C-Jun NH₂-Terminal Kinase Activation

Yicun Wu,

Affiliation Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Key Laboratory of Thrombosis and Hemostasis, Ministry of Health, Suzhou, China
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Jin Dai,

Affiliation School of Life Sciences, Peking University, Beijing, China
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Weilin Zhang,

Affiliation Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Key Laboratory of Thrombosis and Hemostasis, Ministry of Health, Suzhou, China
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Rong Yan,

Affiliation Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Key Laboratory of Thrombosis and Hemostasis, Ministry of Health, Suzhou, China
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Yiwen Zhang,

Affiliation Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Key Laboratory of Thrombosis and Hemostasis, Ministry of Health, Suzhou, China
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Changgeng Ruan,

Affiliation Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Key Laboratory of Thrombosis and Hemostasis, Ministry of Health, Suzhou, China
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Kesheng Dai

* E-mail: kdai@suda.edu.cn

Affiliation Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Key Laboratory of Thrombosis and Hemostasis, Ministry of Health, Suzhou, China
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Platelets
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Platelet activation
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Apoptosis
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Platelet aggregation
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Cancer treatment
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Mitochondria
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Depolarization
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Thrombocytopenia
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