Comparative Study of Nanosecond Electric Fields In Vitro and In Vivo on Hepatocellular Carcinoma Indicate Macrophage Infiltration Contribute to Tumor Ablation In Vivo

Xinhua Chen; Shengyong Yin; Chen Hu; Xinmei Chen; Kai Jiang; Shuming Ye; Xiaowen Feng; Shifeng Fan; Haiyang Xie; Lin Zhou; Shusen Zheng

doi:10.1371/journal.pone.0086421

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Peer-reviewed

Research Article

Comparative Study of Nanosecond Electric Fields In Vitro and In Vivo on Hepatocellular Carcinoma Indicate Macrophage Infiltration Contribute to Tumor Ablation In Vivo

Xinhua Chen ,

Contributed equally to this work with: Xinhua Chen, Shengyong Yin, Chen Hu

Affiliation Key Lab of Combined Multi-organ Transplantation, Ministry of Public Health, The Department of Hepatobiliary and Pancreatic Surgery. The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang Province, China
⨯
Shengyong Yin ,

Contributed equally to this work with: Xinhua Chen, Shengyong Yin, Chen Hu

Affiliation Key Lab of Combined Multi-organ Transplantation, Ministry of Public Health, The Department of Hepatobiliary and Pancreatic Surgery. The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang Province, China
⨯
Chen Hu ,

Contributed equally to this work with: Xinhua Chen, Shengyong Yin, Chen Hu

Affiliation Key Lab of Combined Multi-organ Transplantation, Ministry of Public Health, The Department of Hepatobiliary and Pancreatic Surgery. The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang Province, China
⨯
Xinmei Chen,

Affiliation The Department of Pharmacy, Shandong Traditional Chinese Medicine University, Jinan, Shandong Province, China
⨯
Kai Jiang,

Affiliation Colleges of Biomedical Engineering and Instrument Science, Zhejiang University, Hangzhou, Zhejiang Province, China
⨯
Shuming Ye,

Affiliation Colleges of Biomedical Engineering and Instrument Science, Zhejiang University, Hangzhou, Zhejiang Province, China
⨯
Xiaowen Feng,

Affiliation Key Lab of Combined Multi-organ Transplantation, Ministry of Public Health, The Department of Hepatobiliary and Pancreatic Surgery. The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang Province, China
⨯
Shifeng Fan,

Affiliation Xinjiang Nanosecond Pulse Technology Institute, Urumqi, Xinjiang, China
⨯
Haiyang Xie,

Affiliation Key Lab of Combined Multi-organ Transplantation, Ministry of Public Health, The Department of Hepatobiliary and Pancreatic Surgery. The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang Province, China
⨯
Lin Zhou,

Affiliation Key Lab of Combined Multi-organ Transplantation, Ministry of Public Health, The Department of Hepatobiliary and Pancreatic Surgery. The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang Province, China
⨯
Shusen Zheng

* E-mail: shusenzheng@zju.edu.cn

Affiliation Key Lab of Combined Multi-organ Transplantation, Ministry of Public Health, The Department of Hepatobiliary and Pancreatic Surgery. The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang Province, China
⨯

Comparative Study of Nanosecond Electric Fields In Vitro and In Vivo on Hepatocellular Carcinoma Indicate Macrophage Infiltration Contribute to Tumor Ablation In Vivo

Xinhua Chen,
Shengyong Yin,
Chen Hu,
Xinmei Chen,
Kai Jiang,
Shuming Ye,
Xiaowen Feng,
Shifeng Fan,
Haiyang Xie,
Lin Zhou

Published: January 27, 2014
https://doi.org/10.1371/journal.pone.0086421

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