Phospholipase C-β1 and β4 Contribute to Non-Genetic Cell-to-Cell Variability in Histamine-Induced Calcium Signals in HeLa Cells

• Sachiko Ishida,

  Current address: Laboratory for Cell Signaling Dynamics, RIKEN Quantitative Biology Center, Osaka, Japan

  Affiliation Laboratory for Developmental Neurobiology, RIKEN Brain Science Institute, Wako, Japan

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• Toru Matsu-ura,

  Current address: Department of Molecular and Cellular Physiology, University of Cincinnati, Cincinnati, Ohio, United States of America

  Affiliation Laboratory for Developmental Neurobiology, RIKEN Brain Science Institute, Wako, Japan

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• Kiyoko Fukami,

  Affiliation Laboratory of Genome and Biosignal, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan

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• Takayuki Michikawa ,

  * E-mail: t-michikawa@brain.riken.jp (TM); mikosiba@brain.riken.jp (KM)

  Affiliations Laboratory for Developmental Neurobiology, RIKEN Brain Science Institute, Wako, Japan, Calcium Oscillation Project, ICORP-SORST, Japan Science and Technology Agency, Kawaguchi, Japan, Laboratory for Behavioral Genetics, RIKEN Brain Science Institute, Wako, Japan

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• Katsuhiko Mikoshiba

  * E-mail: t-michikawa@brain.riken.jp (TM); mikosiba@brain.riken.jp (KM)

  Affiliations Laboratory for Developmental Neurobiology, RIKEN Brain Science Institute, Wako, Japan, Calcium Oscillation Project, ICORP-SORST, Japan Science and Technology Agency, Kawaguchi, Japan

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