Deletion of Individual Ku Subunits in Mice Causes an NHEJ-Independent Phenotype Potentially by Altering Apurinic/Apyrimidinic Site Repair

• Yong Jun Choi,

  Current address: Genetics and Molecular Biology Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America

  Affiliation Department of Molecular Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America

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• Han Li,

  Current address: Tumor Suppression Group, Spanish National Cancer Research Centre (CNIO), Madrid, Spain

  Affiliation Department of Molecular Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America

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• Mi Young Son,

  Affiliation Department of Molecular Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America

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• Xiao-hong Wang,

  Affiliation Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America

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• Jamie L. Fornsaglio,

  Current address: Division of Natural Health Science, Seton Hill University, One Seton Drive, Greensburg, Pennsylvania, United States of America

  Affiliation Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America

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• Robert W. Sobol,

  Affiliations Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America, Hillman Cancer Center, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, United States of America, Department of Human Genetics, University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania, United States of America

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• Moonsook Lee,

  Affiliation Department of Genetics, Albert Einstein College of Medicine, Bronx, New York, United States of America

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• Jan Vijg,

  Affiliation Department of Genetics, Albert Einstein College of Medicine, Bronx, New York, United States of America

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• Sandra Imholz,

  Affiliation Center for Health Protection, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands

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• Martijn E. T. Dollé,

  Affiliation Center for Health Protection, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands

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• Harry van Steeg,

  Affiliation Center for Health Protection, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands

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• Erwin Reiling,

  Affiliations Center for Health Protection, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands, MGC Department of Cell Biology and Genetics, Center for Biomedical Genetics, Erasmus MC, Rotterdam, The Netherlands

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• Paul Hasty

  * E-mail: hastye@uthscsa.edu

  Affiliation Department of Molecular Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America

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