Critical Amino Acids within the Human Immunodeficiency Virus Type 1 Envelope Glycoprotein V4 N- and C-Terminals Contribute to Virus Entry

• Yan Li ,

  Contributed equally to this work with: Yan Li, Dan Yang

  Affiliations Department of Microbiology, Harbin Medical University, Harbin, China, Heilongjiang Provincial Key Laboratory for Infection and Immunity, Key Laboratory of Etiology of Heilongjiang Province Education Bureau, Harbin, China

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• Dan Yang ,

  Contributed equally to this work with: Yan Li, Dan Yang

  Affiliation Department of Forensic Medicine, Harbin Medical University, Harbin, China

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• Jia-Ye Wang,

  Affiliations Department of Microbiology, Harbin Medical University, Harbin, China, Heilongjiang Provincial Key Laboratory for Infection and Immunity, Key Laboratory of Etiology of Heilongjiang Province Education Bureau, Harbin, China

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• Yuan Yao,

  Affiliation Academy of Fundamental and Interdisciplinary Science, Harbin Institute of Technology, Harbin, China

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• Wei-Zhe Zhang,

  Affiliations Department of Parasitology, Harbin Medical University, Harbin, China, Heilongjiang Provincial Key Laboratory for Infection and Immunity, Key Laboratory of Etiology of Heilongjiang Province Education Bureau, Harbin, China

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• Lu-Jing Wang,

  Affiliation Department of Biochemistry, Harbin Medical University, Harbin, China

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• De-Chun Cheng,

  Affiliations Department of Parasitology, Harbin Medical University, Harbin, China, Heilongjiang Provincial Key Laboratory for Infection and Immunity, Key Laboratory of Etiology of Heilongjiang Province Education Bureau, Harbin, China

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• Feng-Kun Yang,

  Affiliations Department of Parasitology, Harbin Medical University, Harbin, China, Heilongjiang Provincial Key Laboratory for Infection and Immunity, Key Laboratory of Etiology of Heilongjiang Province Education Bureau, Harbin, China

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• Feng-Min Zhang,

  Affiliations Department of Microbiology, Harbin Medical University, Harbin, China, Heilongjiang Provincial Key Laboratory for Infection and Immunity, Key Laboratory of Etiology of Heilongjiang Province Education Bureau, Harbin, China

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• Min Zhuang ,

  * E-mail: lingh@ems.hrbmu.edu.cn (HL); zhuangm@ems.hrbmu.edu.cn (MZ)

  Affiliations Department of Microbiology, Harbin Medical University, Harbin, China, Heilongjiang Provincial Key Laboratory for Infection and Immunity, Key Laboratory of Etiology of Heilongjiang Province Education Bureau, Harbin, China

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• Hong Ling

  * E-mail: lingh@ems.hrbmu.edu.cn (HL); zhuangm@ems.hrbmu.edu.cn (MZ)

  Affiliations Department of Microbiology, Harbin Medical University, Harbin, China, Department of Parasitology, Harbin Medical University, Harbin, China, Heilongjiang Provincial Key Laboratory for Infection and Immunity, Key Laboratory of Etiology of Heilongjiang Province Education Bureau, Harbin, China

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