Crystal Structures of HIV-1 gp120 Envelope Glycoprotein in Complex with NBD Analogues That Target the CD4-Binding Site

Young Do Kwon; Judith M. LaLonde; Yongping Yang; Mark A. Elban; Akihiro Sugawara; Joel R. Courter; David M. Jones; Amos B. Smith III; Asim K. Debnath; Peter D. Kwong

doi:10.1371/journal.pone.0085940

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Peer-reviewed

Research Article

Crystal Structures of HIV-1 gp120 Envelope Glycoprotein in Complex with NBD Analogues That Target the CD4-Binding Site

Young Do Kwon,

Affiliation Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Judith M. LaLonde,

Affiliation Department of Chemistry, Bryn Mawr College, Bryn Mawr, Pennsylvania, United States of America
⨯
Yongping Yang,

Affiliation Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Mark A. Elban,

Affiliation Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Akihiro Sugawara,

Affiliation Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Joel R. Courter,

Affiliation Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
David M. Jones,

Affiliation Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Amos B. Smith III,

Affiliation Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Asim K. Debnath,

Affiliation Laboratory of Molecular Modeling and Drug Design, Lindsey F. Kimball Research Institute of the New York Blood Center, New York, New York, United States of America
⨯
Peter D. Kwong

* E-mail: pdkwong@nih.gov

Affiliation Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
⨯

Crystal Structures of HIV-1 gp120 Envelope Glycoprotein in Complex with NBD Analogues That Target the CD4-Binding Site

Young Do Kwon,
Judith M. LaLonde,
Yongping Yang,
Mark A. Elban,
Akihiro Sugawara,
Joel R. Courter,
David M. Jones,
Amos B. Smith III,
Asim K. Debnath,
Peter D. Kwong

Published: January 28, 2014
https://doi.org/10.1371/journal.pone.0085940

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