Arctigenin Inhibits Osteoclast Differentiation and Function by Suppressing Both Calcineurin-Dependent and Osteoblastic Cell-Dependent NFATc1 Pathways

• Teruhito Yamashita ,

  * E-mail: teru@po.mdu.ac.jp

  Affiliation Institute for Oral Science, Matsumoto Dental University, Shiojiri, Nagano, Japan

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• Shunsuke Uehara,

  Affiliation Department of Biochemistry, Matsumoto Dental University, Shiojiri, Nagano, Japan

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• Nobuyuki Udagawa,

  Affiliation Department of Biochemistry, Matsumoto Dental University, Shiojiri, Nagano, Japan

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• Feng Li,

  Affiliation Institute of Natural Medicine, University of Toyama, Toyama, Japan

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• Shigetoshi Kadota,

  Affiliation Institute of Natural Medicine, University of Toyama, Toyama, Japan

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• Hiroyasu Esumi,

  Affiliation National Cancer Center Hospital East, Kashiwa, Chiba, Japan

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• Yasuhiro Kobayashi,

  Affiliation Institute for Oral Science, Matsumoto Dental University, Shiojiri, Nagano, Japan

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• Naoyuki Takahashi

  Affiliation Institute for Oral Science, Matsumoto Dental University, Shiojiri, Nagano, Japan

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