Simvastatin Inhibits Glucose Metabolism and Legumain Activity in Human Myotubes

Robert Smith; Rigmor Solberg; Linn Løkken Jacobsen; Anette Larsen Voreland; Arild Christian Rustan; G. Hege Thoresen; Harald Thidemann Johansen

doi:10.1371/journal.pone.0085721

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Open Access

Peer-reviewed

Research Article

Simvastatin Inhibits Glucose Metabolism and Legumain Activity in Human Myotubes

Robert Smith ,

* E-mail: robert.smith@farmasi.uio.no

Current address: Department of Pharmaceutical Biosciences, School of Pharmacy, University of Oslo, Oslo, Norway

Affiliation Department of Pharmaceutical Biosciences, School of Pharmacy, Faculty of Mathematics and Natural Sciences, University of Oslo, Oslo, Norway
⨯
Rigmor Solberg,

Affiliation Department of Pharmaceutical Biosciences, School of Pharmacy, Faculty of Mathematics and Natural Sciences, University of Oslo, Oslo, Norway
⨯
Linn Løkken Jacobsen,

Affiliation Department of Pharmaceutical Biosciences, School of Pharmacy, Faculty of Mathematics and Natural Sciences, University of Oslo, Oslo, Norway
⨯
Anette Larsen Voreland,

Affiliation Department of Pharmaceutical Biosciences, School of Pharmacy, Faculty of Mathematics and Natural Sciences, University of Oslo, Oslo, Norway
⨯
Arild Christian Rustan,

Affiliation Department of Pharmaceutical Biosciences, School of Pharmacy, Faculty of Mathematics and Natural Sciences, University of Oslo, Oslo, Norway
⨯
G. Hege Thoresen,

Affiliations Department of Pharmaceutical Biosciences, School of Pharmacy, Faculty of Mathematics and Natural Sciences, University of Oslo, Oslo, Norway, Department of Pharmacology, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo and Oslo University Hospital, Oslo, Norway
⨯
Harald Thidemann Johansen

Affiliation Department of Pharmacology, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo and Oslo University Hospital, Oslo, Norway
⨯

Simvastatin Inhibits Glucose Metabolism and Legumain Activity in Human Myotubes

Robert Smith,
Rigmor Solberg,
Linn Løkken Jacobsen,
Anette Larsen Voreland,
Arild Christian Rustan,
G. Hege Thoresen,
Harald Thidemann Johansen

Published: January 8, 2014
https://doi.org/10.1371/journal.pone.0085721

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Cell differentiation
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