Effects of Baseline CSF α-Synuclein on Regional Brain Atrophy Rates in Healthy Elders, Mild Cognitive Impairment and Alzheimer’s Disease

Niklas Mattsson; Philip Insel; Duygu Tosun; Jing Zhang; Clifford R. Jack Jr; Douglas Galasko; Michael Weiner; for the Alzheimer’s Disease Neuroimaging Initiative

doi:10.1371/journal.pone.0085443

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Open Access

Peer-reviewed

Research Article

Effects of Baseline CSF α-Synuclein on Regional Brain Atrophy Rates in Healthy Elders, Mild Cognitive Impairment and Alzheimer’s Disease

Niklas Mattsson ,

* E-mail: niklas.mattsson@neuro.gu.se

Affiliations Department of Veterans Affairs Medical Center, Center for Imaging of Neurodegenerative Diseases, San Francisco, California, United States of America, Clinical Neurochemistry Laboratory, Institute of Neuroscience and Physiology, the Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden, Department of Radiology and Biomedical Imaging, University of California, San Francisco, California, United States of America
⨯
Philip Insel,

Affiliation Department of Veterans Affairs Medical Center, Center for Imaging of Neurodegenerative Diseases, San Francisco, California, United States of America
⨯
Duygu Tosun,

Affiliations Department of Veterans Affairs Medical Center, Center for Imaging of Neurodegenerative Diseases, San Francisco, California, United States of America, Department of Radiology and Biomedical Imaging, University of California, San Francisco, California, United States of America
⨯
Jing Zhang,

Affiliation Department of Pathology, University of Washington, Seattle, WA, United States of America
⨯
Clifford R. Jack Jr,

Affiliation Department of Radiology, Mayo Clinic, Rochester, Minnesota, United States of America
⨯
Douglas Galasko,

Affiliation Department of Neurosciences, University of California, San Diego, California, United States of America
⨯
Michael Weiner,

Affiliations Department of Veterans Affairs Medical Center, Center for Imaging of Neurodegenerative Diseases, San Francisco, California, United States of America, Department of Radiology and Biomedical Imaging, University of California, San Francisco, California, United States of America
⨯
for the Alzheimer’s Disease Neuroimaging Initiative

¶A complete list of ADNI investigators can be found at http://adni.loni.usc.edu/wp-content/uploads/how_to_apply/ADNI_Acknowledgement_List.pdf
⨯

Effects of Baseline CSF α-Synuclein on Regional Brain Atrophy Rates in Healthy Elders, Mild Cognitive Impairment and Alzheimer’s Disease

Niklas Mattsson,
Philip Insel,
Duygu Tosun,
Jing Zhang,
Clifford R. Jack Jr,
Douglas Galasko,
Michael Weiner,
for the Alzheimer’s Disease Neuroimaging Initiative

Published: December 31, 2013
https://doi.org/10.1371/journal.pone.0085443

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