Development of a Highly Sensitive and Specific Method for Detection of Circulating Tumor Cells Harboring Somatic Mutations in Non-Small-Cell Lung Cancer Patients

• Frank Breitenbuecher ,

  * E-mail: Frank.Breitenbuecher@uk-essen.de

  Affiliation Department of Medical Oncology, West German Cancer Center, University Hospital Essen, University Duisburg-Essen, Essen, Germany

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• Sandra Hoffarth,

  Affiliation Department of Medical Oncology, West German Cancer Center, University Hospital Essen, University Duisburg-Essen, Essen, Germany

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• Karl Worm,

  Affiliation Institute of Pathology, West German Cancer Center, University Hospital Essen, University Duisburg-Essen, Essen, Germany

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• Diana Cortes-Incio,

  Affiliation Department of Medical Oncology, West German Cancer Center, University Hospital Essen, University Duisburg-Essen, Essen, Germany

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• Thomas C. Gauler,

  Affiliations Department of Medical Oncology, West German Cancer Center, University Hospital Essen, University Duisburg-Essen, Essen, Germany, Division of Thoracic Oncology, Ruhrlandklinik, West German Lung Center, University Duisburg-Essen, Essen, Germany

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• Jens Köhler,

  Affiliation Department of Medical Oncology, West German Cancer Center, University Hospital Essen, University Duisburg-Essen, Essen, Germany

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• Thomas Herold,

  Affiliations Institute of Pathology, West German Cancer Center, University Hospital Essen, University Duisburg-Essen, Essen, Germany, German Cancer Research Center, Heidelberg, Germany, German Cancer Consortium (DKTK), Heidelberg, Germany

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• Kurt Werner Schmid,

  Affiliation Institute of Pathology, West German Cancer Center, University Hospital Essen, University Duisburg-Essen, Essen, Germany

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• Lutz Freitag,

  Affiliation Division of Interventional Pneumology, Ruhrlandklinik, West German Lung Center, University Duisburg-Essen, Essen, Germany

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• Stefan Kasper,

  Affiliation Department of Medical Oncology, West German Cancer Center, University Hospital Essen, University Duisburg-Essen, Essen, Germany

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• Martin Schuler

  Affiliations Department of Medical Oncology, West German Cancer Center, University Hospital Essen, University Duisburg-Essen, Essen, Germany, Division of Thoracic Oncology, Ruhrlandklinik, West German Lung Center, University Duisburg-Essen, Essen, Germany, German Cancer Consortium (DKTK), Heidelberg, Germany

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