Interleukin-6 Modulation of Intestinal Epithelial Tight Junction Permeability Is Mediated by JNK Pathway Activation of Claudin-2 Gene

Rana Al-Sadi; Dongmei Ye; Michel Boivin; Shuhong Guo; Mariam Hashimi; Lisa Ereifej; Thomas Y. Ma

doi:10.1371/journal.pone.0085345

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Peer-reviewed

Research Article

Interleukin-6 Modulation of Intestinal Epithelial Tight Junction Permeability Is Mediated by JNK Pathway Activation of Claudin-2 Gene

Rana Al-Sadi ,

Contributed equally to this work with: Rana Al-Sadi, Dongmei Ye

Affiliations Department of Internal Medicine, University of New Mexico School of Medicine, Albuquerque, New Mexico, United States of America, Albuquerque Veterans Affairs Medical Center, Albuquerque, New Mexico, United States of America
⨯
Dongmei Ye ,

Contributed equally to this work with: Rana Al-Sadi, Dongmei Ye

Affiliation Department of Internal Medicine, University of New Mexico School of Medicine, Albuquerque, New Mexico, United States of America
⨯
Michel Boivin,

Affiliation Department of Internal Medicine, University of New Mexico School of Medicine, Albuquerque, New Mexico, United States of America
⨯
Shuhong Guo,

Affiliations Department of Internal Medicine, University of New Mexico School of Medicine, Albuquerque, New Mexico, United States of America, Albuquerque Veterans Affairs Medical Center, Albuquerque, New Mexico, United States of America
⨯
Mariam Hashimi,

Affiliation Department of Internal Medicine, University of New Mexico School of Medicine, Albuquerque, New Mexico, United States of America
⨯
Lisa Ereifej,

Affiliation Department of Internal Medicine, University of New Mexico School of Medicine, Albuquerque, New Mexico, United States of America
⨯
Thomas Y. Ma

* E-mail: tma@salud.unm.edu

Affiliations Department of Internal Medicine, University of New Mexico School of Medicine, Albuquerque, New Mexico, United States of America, Albuquerque Veterans Affairs Medical Center, Albuquerque, New Mexico, United States of America
⨯

Interleukin-6 Modulation of Intestinal Epithelial Tight Junction Permeability Is Mediated by JNK Pathway Activation of Claudin-2 Gene

Rana Al-Sadi,
Dongmei Ye,
Michel Boivin,
Shuhong Guo,
Mariam Hashimi,
Lisa Ereifej,
Thomas Y. Ma

Published: March 24, 2014
https://doi.org/10.1371/journal.pone.0085345

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