Protective Immunity against Lethal F. tularensis holarctica LVS Provided by Vaccination with Selected Novel CD8+ T Cell Epitopes

Open Access

Peer-reviewed

Research Article

Protective Immunity against Lethal F. tularensis holarctica LVS Provided by Vaccination with Selected Novel CD8⁺ T Cell Epitopes

Shahar Rotem ,

Contributed equally to this work with: Shahar Rotem, Ofer Cohen

Affiliation Department of Biochemistry and Molecular Genetics, Israel Institute for Biological Research, Ness-Ziona, Israel
⨯
Ofer Cohen ,

Contributed equally to this work with: Shahar Rotem, Ofer Cohen

Affiliation Department of Biochemistry and Molecular Genetics, Israel Institute for Biological Research, Ness-Ziona, Israel
⨯
Erez Bar-Haim,

Affiliation Department of Biochemistry and Molecular Genetics, Israel Institute for Biological Research, Ness-Ziona, Israel
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Liat Bar-On,

Affiliation Department of Biochemistry and Molecular Genetics, Israel Institute for Biological Research, Ness-Ziona, Israel
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Sharon Ehrlich,

Affiliation Department of Biochemistry and Molecular Genetics, Israel Institute for Biological Research, Ness-Ziona, Israel
⨯
Avigdor Shafferman

* E-mail: avigdors@iibr.gov.il

Affiliation Department of Biochemistry and Molecular Genetics, Israel Institute for Biological Research, Ness-Ziona, Israel
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Cytotoxic T cells
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Francisella tularensis
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T cells
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Mouse models
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Vaccination and immunization
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Vaccines
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Immune response
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Bacterial lethality
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