Microcystin-LR Induced Reactive Oxygen Species Mediate Cytoskeletal Disruption and Apoptosis of Hepatocytes in Cyprinus carpio L.

Jinlin Jiang; Zhengjun Shan; Weili Xu; Xiaorong Wang; Junying Zhou; Deyang Kong; Jing Xu

doi:10.1371/journal.pone.0084768

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Open Access

Peer-reviewed

Research Article

Microcystin-LR Induced Reactive Oxygen Species Mediate Cytoskeletal Disruption and Apoptosis of Hepatocytes in Cyprinus carpio L.

Jinlin Jiang ,

* E-mail: jjl@nies.org

Affiliation Nanjing Institute of Environmental Sciences/Key Laboratory of Pesticide Environmental Assessment and Pollution Control, Ministry of Environmental Protection, Nanjing, People’s Republic of China
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Zhengjun Shan,

Affiliation Nanjing Institute of Environmental Sciences/Key Laboratory of Pesticide Environmental Assessment and Pollution Control, Ministry of Environmental Protection, Nanjing, People’s Republic of China
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Weili Xu,

Affiliation Nanjing Institute of Environmental Sciences/Key Laboratory of Pesticide Environmental Assessment and Pollution Control, Ministry of Environmental Protection, Nanjing, People’s Republic of China
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Xiaorong Wang,

Affiliation State Key Laboratory of Pollution Control and Resource Reuse, School of the Environment, Nanjing University, Nanjing, People’s Republic of China
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Junying Zhou,

Affiliation Nanjing Institute of Environmental Sciences/Key Laboratory of Pesticide Environmental Assessment and Pollution Control, Ministry of Environmental Protection, Nanjing, People’s Republic of China
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Deyang Kong,

Affiliation Nanjing Institute of Environmental Sciences/Key Laboratory of Pesticide Environmental Assessment and Pollution Control, Ministry of Environmental Protection, Nanjing, People’s Republic of China
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Jing Xu

Affiliation Nanjing Institute of Environmental Sciences/Key Laboratory of Pesticide Environmental Assessment and Pollution Control, Ministry of Environmental Protection, Nanjing, People’s Republic of China
⨯

Microcystin-LR Induced Reactive Oxygen Species Mediate Cytoskeletal Disruption and Apoptosis of Hepatocytes in Cyprinus carpio L.

Jinlin Jiang,
Zhengjun Shan,
Weili Xu,
Xiaorong Wang,
Junying Zhou,
Deyang Kong,
Jing Xu

Published: December 20, 2013
https://doi.org/10.1371/journal.pone.0084768

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Cytoskeleton
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Carps
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Oxidative stress
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Reactive oxygen species
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