BRAFV600E Mutation Analysis in Patients with Metastatic Colorectal Cancer (mCRC) in Daily Clinical Practice: Correlations with Clinical Characteristics, and Its Impact on Patients’ Outcome

Zacharenia Saridaki; Maria Tzardi; Maria Sfakianaki; Chara Papadaki; Alexandra Voutsina; Aristea Kalykaki; Ippokratis Messaritakis; Kyriakos Mpananis; Dimitris Mavroudis; Efstathios Stathopoulos; Vassilis Georgoulias; John Souglakos

doi:10.1371/journal.pone.0084604

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Peer-reviewed

Research Article

BRAFV600E Mutation Analysis in Patients with Metastatic Colorectal Cancer (mCRC) in Daily Clinical Practice: Correlations with Clinical Characteristics, and Its Impact on Patients’ Outcome

Zacharenia Saridaki,

Affiliations Laboratory of Tumor Cell Biology, School of Medicine, University of Crete, Heraklion, Crete, Greece, Department of Medical Oncology, University General Hospital, Heraklion, Crete, Greece
⨯
Maria Tzardi,

Affiliation Laboratory of Pathology, University General Hospital, Heraklion, Crete, Greece
⨯
Maria Sfakianaki,

Affiliation Laboratory of Tumor Cell Biology, School of Medicine, University of Crete, Heraklion, Crete, Greece
⨯
Chara Papadaki,

Affiliation Laboratory of Tumor Cell Biology, School of Medicine, University of Crete, Heraklion, Crete, Greece
⨯
Alexandra Voutsina,

Affiliation Laboratory of Tumor Cell Biology, School of Medicine, University of Crete, Heraklion, Crete, Greece
⨯
Aristea Kalykaki,

Affiliation Laboratory of Tumor Cell Biology, School of Medicine, University of Crete, Heraklion, Crete, Greece
⨯
Ippokratis Messaritakis,

Affiliation Laboratory of Tumor Cell Biology, School of Medicine, University of Crete, Heraklion, Crete, Greece
⨯
Kyriakos Mpananis,

Affiliation Laboratory of Tumor Cell Biology, School of Medicine, University of Crete, Heraklion, Crete, Greece
⨯
Dimitris Mavroudis,

Affiliations Laboratory of Tumor Cell Biology, School of Medicine, University of Crete, Heraklion, Crete, Greece, Department of Medical Oncology, University General Hospital, Heraklion, Crete, Greece
⨯
Efstathios Stathopoulos,

Affiliation Laboratory of Pathology, University General Hospital, Heraklion, Crete, Greece
⨯
Vassilis Georgoulias,

Affiliations Laboratory of Tumor Cell Biology, School of Medicine, University of Crete, Heraklion, Crete, Greece, Department of Medical Oncology, University General Hospital, Heraklion, Crete, Greece
⨯
John Souglakos

* E-mail: georgsec@med.uoc.gr

Affiliations Laboratory of Tumor Cell Biology, School of Medicine, University of Crete, Heraklion, Crete, Greece, Department of Medical Oncology, University General Hospital, Heraklion, Crete, Greece
⨯

BRAFV600E Mutation Analysis in Patients with Metastatic Colorectal Cancer (mCRC) in Daily Clinical Practice: Correlations with Clinical Characteristics, and Its Impact on Patients’ Outcome

Zacharenia Saridaki,
Maria Tzardi,
Maria Sfakianaki,
Chara Papadaki,
Alexandra Voutsina,
Aristea Kalykaki,
Ippokratis Messaritakis,
Kyriakos Mpananis,
Dimitris Mavroudis,
Efstathios Stathopoulos

Published: December 18, 2013
https://doi.org/10.1371/journal.pone.0084604

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Colorectal cancer
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Substitution mutation
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