Structure Based Identification and Characterization of Flavonoids That Disrupt Human Papillomavirus-16 E6 Function

Jonathan J. Cherry; Anne Rietz; Anna Malinkevich; Yuqi Liu; Meng Xie; Matthew Bartolowits; V. Jo Davisson; James D. Baleja; Elliot J. Androphy

doi:10.1371/journal.pone.0084506

Loading metrics

Open Access

Peer-reviewed

Research Article

Structure Based Identification and Characterization of Flavonoids That Disrupt Human Papillomavirus-16 E6 Function

Jonathan J. Cherry,

Affiliations Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America, Department of Dermatology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
⨯
Anne Rietz,

Affiliation Department of Dermatology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
⨯
Anna Malinkevich,

Affiliation Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
⨯
Yuqi Liu,

Affiliation Department of Biochemistry, Tufts University School of Medicine, Boston, Massachusetts, United States of America
⨯
Meng Xie,

Affiliations Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America, Department of Dermatology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
⨯
Matthew Bartolowits,

Affiliation Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University College of Pharmacy, West Lafayette, Indiana, United States of America
⨯
V. Jo Davisson,

Affiliation Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University College of Pharmacy, West Lafayette, Indiana, United States of America
⨯
James D. Baleja,

Affiliation Department of Biochemistry, Tufts University School of Medicine, Boston, Massachusetts, United States of America
⨯
Elliot J. Androphy

* E-mail: eandro@iu.edu

Affiliations Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America, Department of Dermatology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
⨯

Structure Based Identification and Characterization of Flavonoids That Disrupt Human Papillomavirus-16 E6 Function

Jonathan J. Cherry,
Anne Rietz,
Anna Malinkevich,
Yuqi Liu,
Meng Xie,
Matthew Bartolowits,
V. Jo Davisson,
James D. Baleja,
Elliot J. Androphy

Published: December 23, 2013
https://doi.org/10.1371/journal.pone.0084506

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Binding analysis
Is the Subject Area "Binding analysis" applicable to this article?

Thanks for your feedback.
Drug interactions
Is the Subject Area "Drug interactions" applicable to this article?

Thanks for your feedback.
HPV-16
Is the Subject Area "HPV-16" applicable to this article?

Thanks for your feedback.
Human papillomavirus
Is the Subject Area "Human papillomavirus" applicable to this article?

Thanks for your feedback.
Cervical cancer
Is the Subject Area "Cervical cancer" applicable to this article?

Thanks for your feedback.
Cancer treatment
Is the Subject Area "Cancer treatment" applicable to this article?

Thanks for your feedback.
Cell immortalization
Is the Subject Area "Cell immortalization" applicable to this article?

Thanks for your feedback.
Human papillomavirus infection
Is the Subject Area "Human papillomavirus infection" applicable to this article?

Thanks for your feedback.