Myeloid Cell Sirtuin-1 Expression Does Not Alter Host Immune Responses to Gram-Negative Endotoxemia or Gram-Positive Bacterial Infection

Laura E. Crotty Alexander; Brenda J. Marsh; Anjuli M. Timmer; Ann E. Lin; Kayvan Zainabadi; Agnieszka Czopik; Leonard Guarente; Victor Nizet

doi:10.1371/journal.pone.0084481

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Open Access

Peer-reviewed

Research Article

Myeloid Cell Sirtuin-1 Expression Does Not Alter Host Immune Responses to Gram-Negative Endotoxemia or Gram-Positive Bacterial Infection

Laura E. Crotty Alexander ,

* E-mail: lcrotty@ucsd.edu

Affiliations Pulmonary Critical Care Section, Veterans Affairs San Diego Healthcare System, San Diego, California, United States of America, Department of Medicine, University of California San Diego, San Diego, California, United States of America
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Brenda J. Marsh,

Affiliations Pulmonary Critical Care Section, Veterans Affairs San Diego Healthcare System, San Diego, California, United States of America, Department of Medicine, University of California San Diego, San Diego, California, United States of America
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Anjuli M. Timmer,

Affiliation Department of Pediatrics, University of California San Diego, San Diego, California, United States of America
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Ann E. Lin,

Affiliation Department of Pediatrics, University of California San Diego, San Diego, California, United States of America
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Kayvan Zainabadi,

Affiliation Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
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Agnieszka Czopik,

Affiliation Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
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Leonard Guarente,

Affiliation Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
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Victor Nizet

Affiliations Department of Pediatrics, University of California San Diego, San Diego, California, United States of America, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, San Diego, California, United States of America
⨯

Myeloid Cell Sirtuin-1 Expression Does Not Alter Host Immune Responses to Gram-Negative Endotoxemia or Gram-Positive Bacterial Infection

Laura E. Crotty Alexander,
Brenda J. Marsh,
Anjuli M. Timmer,
Ann E. Lin,
Kayvan Zainabadi,
Agnieszka Czopik,
Leonard Guarente,
Victor Nizet

Published: December 26, 2013
https://doi.org/10.1371/journal.pone.0084481

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