SIV Vpx Is Essential for Macrophage Infection but Not for Development of AIDS

Susan V. Westmoreland; A. Peter Converse; Kasia Hrecka; Mollie Hurley; Heather Knight; Michael Piatak; Jeffrey Lifson; Keith G. Mansfield; Jacek Skowronski; Ronald C. Desrosiers

doi:10.1371/journal.pone.0084463

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Open Access

Peer-reviewed

Research Article

SIV Vpx Is Essential for Macrophage Infection but Not for Development of AIDS

Susan V. Westmoreland ,

* E-mail: susan_westmoreland@hms.harvard.edu

Affiliation Harvard Medical School, New England Primate Research Center, Division of Comparative Pathology, Southborough, Massachusetts, United States of America
⨯
A. Peter Converse,

Affiliation Harvard Medical School, New England Primate Research Center, Division of Comparative Pathology, Southborough, Massachusetts, United States of America
⨯
Kasia Hrecka,

Affiliation Case Western Reserve University School of Medicine, Department of Molecular Biology and Microbiology, Cleveland, Ohio, United States of America
⨯
Mollie Hurley,

Current address: Stack Veterinary Hospital, Syracuse, New York, United States of America

Affiliation Harvard Medical School, New England Primate Research Center, Division of Comparative Pathology, Southborough, Massachusetts, United States of America
⨯
Heather Knight,

Affiliation Harvard Medical School, New England Primate Research Center, Division of Comparative Pathology, Southborough, Massachusetts, United States of America
⨯
Michael Piatak,

Affiliation AIDS and Cancer Virus Program NCI-Frederick, SAIC-Frederick, Frederick, Maryland, United States of America
⨯
Jeffrey Lifson,

Affiliation AIDS and Cancer Virus Program NCI-Frederick, SAIC-Frederick, Frederick, Maryland, United States of America
⨯
Keith G. Mansfield,

Current address: Novartis, Cambridge, Massachusetts, United States of America

Affiliation Harvard Medical School, New England Primate Research Center, Division of Comparative Pathology, Southborough, Massachusetts, United States of America
⨯
Jacek Skowronski,

Affiliation Case Western Reserve University School of Medicine, Department of Molecular Biology and Microbiology, Cleveland, Ohio, United States of America
⨯
Ronald C. Desrosiers

Affiliation Harvard Medical School, New England Primate Research Center, Division of Microbiology, Southborough, Massachusetts, United States of America
⨯

SIV Vpx Is Essential for Macrophage Infection but Not for Development of AIDS

Susan V. Westmoreland,
A. Peter Converse,
Kasia Hrecka,
Mollie Hurley,
Heather Knight,
Michael Piatak,
Jeffrey Lifson,
Keith G. Mansfield,
Jacek Skowronski,
Ronald C. Desrosiers

Published: January 21, 2014
https://doi.org/10.1371/journal.pone.0084463

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