Requirement of NOX2 Expression in Both Retina and Bone Marrow for Diabetes-Induced Retinal Vascular Injury

Modesto Rojas; Wenbo Zhang; Zhimin Xu; Tahira Lemtalsi; Phillip Chandler; Haroldo A. Toque; Robert W. Caldwell; Ruth B. Caldwell

doi:10.1371/journal.pone.0084357

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Open Access

Peer-reviewed

Research Article

Requirement of NOX2 Expression in Both Retina and Bone Marrow for Diabetes-Induced Retinal Vascular Injury

Modesto Rojas,

Affiliations VA Medical Center, Augusta, Georgia, United States of America, Vascular Biology Center, Georgia Regents University, Augusta, Georgia, United States of America
⨯
Wenbo Zhang,

Current address: Department of Ophthalmology & Visual Sciences, University of Texas Medical Branch, Galveston, Texas, United States of America

Affiliations VA Medical Center, Augusta, Georgia, United States of America, Vascular Biology Center, Georgia Regents University, Augusta, Georgia, United States of America
⨯
Zhimin Xu,

Affiliations VA Medical Center, Augusta, Georgia, United States of America, Vascular Biology Center, Georgia Regents University, Augusta, Georgia, United States of America
⨯
Tahira Lemtalsi,

Affiliations VA Medical Center, Augusta, Georgia, United States of America, Vascular Biology Center, Georgia Regents University, Augusta, Georgia, United States of America
⨯
Phillip Chandler,

Affiliation Immunotherapy Center, Georgia Reagents University, Augusta, Georgia, United States of America
⨯
Haroldo A. Toque,

Affiliation Department of Pharmacology & Toxicology, Georgia Reagents University, Augusta, Georgia, United States of America
⨯
Robert W. Caldwell,

Affiliation Department of Pharmacology & Toxicology, Georgia Reagents University, Augusta, Georgia, United States of America
⨯
Ruth B. Caldwell

* E-mail: rcaldwel@gru.edu

Affiliations VA Medical Center, Augusta, Georgia, United States of America, Vascular Biology Center, Georgia Regents University, Augusta, Georgia, United States of America
⨯

Requirement of NOX2 Expression in Both Retina and Bone Marrow for Diabetes-Induced Retinal Vascular Injury

Modesto Rojas,
Wenbo Zhang,
Zhimin Xu,
Tahira Lemtalsi,
Phillip Chandler,
Haroldo A. Toque,
Robert W. Caldwell,
Ruth B. Caldwell

Published: December 17, 2013
https://doi.org/10.1371/journal.pone.0084357

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Diabetes mellitus
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White blood cells
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Retina
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Retinal vessels
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Superoxides
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Vascular permeability
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Bone marrow cells
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Diabetic retinopathy
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