HIV-1 Env DNA Vaccine plus Protein Boost Delivered by EP Expands B- and T-Cell Responses and Neutralizing Phenotype In Vivo

Kar Muthumani; Megan C. Wise; Kate E. Broderick; Natalie Hutnick; Jonathan Goodman; Seleeke Flingai; Jian Yan; Chaoran B. Bian; Janess Mendoza; Colleen Tingey; Christine Wilson; Krzysztof Wojtak; Niranjan Y. Sardesai; David B. Weiner

doi:10.1371/journal.pone.0084234

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Open Access

Peer-reviewed

Research Article

HIV-1 Env DNA Vaccine plus Protein Boost Delivered by EP Expands B- and T-Cell Responses and Neutralizing Phenotype In Vivo

Kar Muthumani ,

* E-mail: muthuman@mail.med.upenn.edu

Affiliation Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Megan C. Wise,

Affiliation Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Kate E. Broderick,

Affiliation Inovio Pharmaceuticals Inc, Blue Bell, Pennsylvania, United States of America
⨯
Natalie Hutnick,

Affiliation Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Jonathan Goodman,

Affiliation Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Seleeke Flingai,

Affiliation Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Jian Yan,

Affiliation Inovio Pharmaceuticals Inc, Blue Bell, Pennsylvania, United States of America
⨯
Chaoran B. Bian,

Affiliation Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Janess Mendoza,

Affiliation Inovio Pharmaceuticals Inc, Blue Bell, Pennsylvania, United States of America
⨯
Colleen Tingey,

Affiliation Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Christine Wilson,

Affiliation Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Krzysztof Wojtak,

Affiliation Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Niranjan Y. Sardesai,

Affiliation Inovio Pharmaceuticals Inc, Blue Bell, Pennsylvania, United States of America
⨯
David B. Weiner

Affiliation Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯

HIV-1 Env DNA Vaccine plus Protein Boost Delivered by EP Expands B- and T-Cell Responses and Neutralizing Phenotype In Vivo

Kar Muthumani,
Megan C. Wise,
Kate E. Broderick,
Natalie Hutnick,
Jonathan Goodman,
Seleeke Flingai,
Jian Yan,
Chaoran B. Bian,
Janess Mendoza,
Colleen Tingey

Published: December 31, 2013
https://doi.org/10.1371/journal.pone.0084234

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