HLA-DQB1*03 Confers Susceptibility to Chronic Hepatitis C in Japanese: A Genome-Wide Association Study

• Daiki Miki ,

  Contributed equally to this work with: Daiki Miki, Hidenori Ochi

  Affiliations Laboratory for Digestive Diseases, Center for Integrative Medical Sciences, RIKEN, Hiroshima, Japan, Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan, Liver Research Project Center, Hiroshima University, Hiroshima, Japan

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• Hidenori Ochi ,

  Contributed equally to this work with: Daiki Miki, Hidenori Ochi

  Affiliations Laboratory for Digestive Diseases, Center for Integrative Medical Sciences, RIKEN, Hiroshima, Japan, Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan, Liver Research Project Center, Hiroshima University, Hiroshima, Japan

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• Atsushi Takahashi,

  Affiliation Laboratory for Statistical Analysis, Center for Integrative Medical Sciences, RIKEN, Yokohama, Japan

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• C. Nelson Hayes,

  Affiliations Laboratory for Digestive Diseases, Center for Integrative Medical Sciences, RIKEN, Hiroshima, Japan, Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan, Liver Research Project Center, Hiroshima University, Hiroshima, Japan

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• Yuji Urabe,

  Affiliation Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan

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• Hiromi Abe,

  Affiliations Laboratory for Digestive Diseases, Center for Integrative Medical Sciences, RIKEN, Hiroshima, Japan, Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan

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• Tomokazu Kawaoka,

  Affiliations Laboratory for Digestive Diseases, Center for Integrative Medical Sciences, RIKEN, Hiroshima, Japan, Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan, Liver Research Project Center, Hiroshima University, Hiroshima, Japan

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• Masataka Tsuge,

  Affiliations Liver Research Project Center, Hiroshima University, Hiroshima, Japan, Natural Science Center for Basic Research and Development, Hiroshima University, Hiroshima, Japan

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• Nobuhiko Hiraga,

  Affiliations Laboratory for Digestive Diseases, Center for Integrative Medical Sciences, RIKEN, Hiroshima, Japan, Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan, Liver Research Project Center, Hiroshima University, Hiroshima, Japan

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• Michio Imamura,

  Affiliations Laboratory for Digestive Diseases, Center for Integrative Medical Sciences, RIKEN, Hiroshima, Japan, Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan, Liver Research Project Center, Hiroshima University, Hiroshima, Japan

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• Yoshiiku Kawakami,

  Affiliations Laboratory for Digestive Diseases, Center for Integrative Medical Sciences, RIKEN, Hiroshima, Japan, Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan, Liver Research Project Center, Hiroshima University, Hiroshima, Japan

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• Hiroshi Aikata,

  Affiliations Laboratory for Digestive Diseases, Center for Integrative Medical Sciences, RIKEN, Hiroshima, Japan, Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan, Liver Research Project Center, Hiroshima University, Hiroshima, Japan

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• Shoichi Takahashi,

  Affiliations Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan, Liver Research Project Center, Hiroshima University, Hiroshima, Japan

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• Norio Akuta,

  Affiliation Department of Hepatology, Toranomon Hospital, Tokyo, Japan

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• Fumitaka Suzuki,

  Affiliation Department of Hepatology, Toranomon Hospital, Tokyo, Japan

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• Kenji Ikeda,

  Affiliation Department of Hepatology, Toranomon Hospital, Tokyo, Japan

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• Hiromitsu Kumada,

  Affiliation Department of Hepatology, Toranomon Hospital, Tokyo, Japan

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• Yoshiyasu Karino,

  Affiliation Department of Gastroenterology, Sapporo Kosei General Hospital, Hokkaido, Japan

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• Joji Toyota,

  Affiliation Department of Gastroenterology, Sapporo Kosei General Hospital, Hokkaido, Japan

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• Tatsuhiko Tsunoda,

  Affiliation Laboratory for Medical Science Mathematics, Center for Integrative Medical Sciences, RIKEN, Yokohama, Japan

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• Michiaki Kubo,

  Affiliation Laboratory for Genotyping Development, Center for Integrative Medical Sciences, RIKEN, Yokohama, Japan

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• Naoyuki Kamatani,

  Affiliation Laboratory for Statistical Analysis, Center for Integrative Medical Sciences, RIKEN, Yokohama, Japan

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• Yusuke Nakamura,

  Affiliation Laboratory of Molecular Medicine, Human Genome Center, The Institute of Medical Science, University of Tokyo, Tokyo, Japan

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•  [ ... ],
• Kazuaki Chayama

  * E-mail: chayama@hiroshima-u.ac.jp

  Affiliations Laboratory for Digestive Diseases, Center for Integrative Medical Sciences, RIKEN, Hiroshima, Japan, Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan, Liver Research Project Center, Hiroshima University, Hiroshima, Japan

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