ERK5 Activation by Gq-Coupled Muscarinic Receptors Is Independent of Receptor Internalization and β-Arrestin Recruitment

Open Access

Peer-reviewed

Research Article

Guzmán Sánchez-Fernández,

Affiliations Departamento de Biología Molecular and Centro de Biología Molecular “Severo Ochoa”, Universidad Autónoma de Madrid, UAM-CSIC, Madrid, Spain, Instituto de Investigación Sanitaria La Princesa, Madrid, Spain
⨯
Sofía Cabezudo,

Affiliations Departamento de Biología Molecular and Centro de Biología Molecular “Severo Ochoa”, Universidad Autónoma de Madrid, UAM-CSIC, Madrid, Spain, Instituto de Investigación Sanitaria La Princesa, Madrid, Spain
⨯
Carlota García-Hoz,

Affiliations Departamento de Biología Molecular and Centro de Biología Molecular “Severo Ochoa”, Universidad Autónoma de Madrid, UAM-CSIC, Madrid, Spain, Instituto de Investigación Sanitaria La Princesa, Madrid, Spain
⨯
Andrew B. Tobin,

Affiliation Medical Research Council Toxicology Unit, University of Leicester, Leicester, United Kingdom
⨯
Federico Mayor Jr ,

* E-mail: fmayor@cbm.uam.es; cribas@cbm.uam.es

Affiliations Departamento de Biología Molecular and Centro de Biología Molecular “Severo Ochoa”, Universidad Autónoma de Madrid, UAM-CSIC, Madrid, Spain, Instituto de Investigación Sanitaria La Princesa, Madrid, Spain
⨯
Catalina Ribas

* E-mail: fmayor@cbm.uam.es; cribas@cbm.uam.es

Affiliations Departamento de Biología Molecular and Centro de Biología Molecular “Severo Ochoa”, Universidad Autónoma de Madrid, UAM-CSIC, Madrid, Spain, Instituto de Investigación Sanitaria La Princesa, Madrid, Spain
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G protein coupled receptors
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Phosphorylation
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Transfection
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CHO cells
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Carbachol
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MAPK signaling cascades
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Fibroblasts
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Muscarinic acetylcholine receptors
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