Detection of Atomic Scale Changes in the Free Volume Void Size of Three-Dimensional Colorectal Cancer Cell Culture Using Positron Annihilation Lifetime Spectroscopy

• Eneko Axpe ,

  Contributed equally to this work with: Eneko Axpe, Tamara Lopez-Euba

  * E-mail: eneko.axpe@ehu.es

  Affiliation Department of Electricity and Electronics, University of the Basque Country - UPV/EHU, Leioa, Basque Country, Spain

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• Tamara Lopez-Euba ,

  Contributed equally to this work with: Eneko Axpe, Tamara Lopez-Euba

  Affiliation Immunogenetics Research Laboratory, BioCruces Research Institute, Barakaldo, Basque Country, Spain

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• Ainara Castellanos-Rubio,

  Affiliations Immunogenetics Research Laboratory, BioCruces Research Institute, Barakaldo, Basque Country, Spain, Department of Genetics, Physical Anthropology and Animal Physiology, University of the Basque Country - UPV/EHU, Leioa, Basque Country, Spain

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• David Merida,

  Affiliation Department of Applied Physics II, University of the Basque Country - UPV/EHU, Leioa, Basque Country, Spain

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• Jose Angel Garcia,

  Affiliation Department of Applied Physics II, University of the Basque Country - UPV/EHU, Leioa, Basque Country, Spain

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• Leticia Plaza-Izurieta,

  Affiliations Immunogenetics Research Laboratory, BioCruces Research Institute, Barakaldo, Basque Country, Spain, Department of Genetics, Physical Anthropology and Animal Physiology, University of the Basque Country - UPV/EHU, Leioa, Basque Country, Spain

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• Nora Fernandez-Jimenez,

  Affiliations Immunogenetics Research Laboratory, BioCruces Research Institute, Barakaldo, Basque Country, Spain, Department of Genetics, Physical Anthropology and Animal Physiology, University of the Basque Country - UPV/EHU, Leioa, Basque Country, Spain

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• Fernando Plazaola ,

  ¶These authors also contributed equally to this work.

  Affiliation Department of Electricity and Electronics, University of the Basque Country - UPV/EHU, Leioa, Basque Country, Spain

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• Jose Ramon Bilbao

  ¶These authors also contributed equally to this work.

  Affiliations Immunogenetics Research Laboratory, BioCruces Research Institute, Barakaldo, Basque Country, Spain, Department of Genetics, Physical Anthropology and Animal Physiology, University of the Basque Country - UPV/EHU, Leioa, Basque Country, Spain

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