Application of Multi-SNP Approaches Bayesian LASSO and AUC-RF to Detect Main Effects of Inflammatory-Gene Variants Associated with Bladder Cancer Risk

• Evangelina López de Maturana ,

  Contributed equally to this work with: Evangelina López de Maturana, Yuanqing Ye

  Affiliation Genetic and Molecular Epidemiology Group, Spanish National Cancer Research Center (CNIO), Madrid, Spain

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• Yuanqing Ye ,

  Contributed equally to this work with: Evangelina López de Maturana, Yuanqing Ye

  Affiliation Department of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

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• M. Luz Calle,

  Affiliation Systems Biology Department, University of Vic, Vic, Spain

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• Nathaniel Rothman,

  Affiliation Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, Bethesda, Maryland, United States of America

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• Víctor Urrea,

  Affiliation Systems Biology Department, University of Vic, Vic, Spain

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• Manolis Kogevinas,

  Affiliations Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain, Institut Municipal d’Investigació Mèdica – Hospital del Mar, Barcelona, Spain

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• Sandra Petrus,

  Affiliations Genetic and Molecular Epidemiology Group, Spanish National Cancer Research Center (CNIO), Madrid, Spain, Systems Biology Department, University of Vic, Vic, Spain

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• Stephen J. Chanock,

  Affiliation Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, Bethesda, Maryland, United States of America

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• Adonina Tardón,

  Affiliation Universidad de Oviedo, Oviedo, Spain

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• Montserrat García-Closas,

  Affiliation Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, Bethesda, Maryland, United States of America

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• Anna González-Neira,

  Affiliation Genetic and Molecular Epidemiology Group, Spanish National Cancer Research Center (CNIO), Madrid, Spain

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• Gemma Vellalta,

  Affiliation Institut Municipal d’Investigació Mèdica – Hospital del Mar, Barcelona, Spain

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• Alfredo Carrato,

  Affiliations Hospital Universitario de Elche, Elche, Spain, Hospital Universitario Ramon y Cajal, Madrid, Spain

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• Arcadi Navarro,

  Affiliations Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Barcelona, Spain, Institut de Biologia Evolutiva (UPF-CSIC), Barcelona, Spain, Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain, Instituto Nacional de Bioinformática, Barcelona, Spain

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• Belén Lorente-Galdós,

  Affiliations Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Barcelona, Spain, Institut de Biologia Evolutiva (UPF-CSIC), Barcelona, Spain, Instituto Nacional de Bioinformática, Barcelona, Spain

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• Debra T. Silverman,

  Affiliation Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, Bethesda, Maryland, United States of America

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• Francisco X. Real,

  Affiliations Genetic and Molecular Epidemiology Group, Spanish National Cancer Research Center (CNIO), Madrid, Spain, Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Barcelona, Spain

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• Xifeng Wu ,

  ¶These authors also contributed equally to this work.

  Affiliation Department of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

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•  [ ... ],
• Núria Malats

  * E-mail: nmalats@cnio.es

  ¶These authors also contributed equally to this work.

  Affiliation Genetic and Molecular Epidemiology Group, Spanish National Cancer Research Center (CNIO), Madrid, Spain

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