Clinical Classification of Cancer Cachexia: Phenotypic Correlates in Human Skeletal Muscle

Neil Johns; Shinji Hatakeyama; Nathan A. Stephens; Martin Degen; Simone Degen; Wilfried Frieauff; Christian Lambert; James A. Ross; Ronenn Roubenoff; David J. Glass; Carsten Jacobi; Kenneth C. H. Fearon

doi:10.1371/journal.pone.0083618

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Open Access

Peer-reviewed

Research Article

Clinical Classification of Cancer Cachexia: Phenotypic Correlates in Human Skeletal Muscle

Neil Johns,

Affiliation Department of Clinical and Surgical Sciences, University of Edinburgh, Edinburgh, United Kingdom
⨯
Shinji Hatakeyama,

Affiliation Novartis Institutes for BioMedical Research Basel, Novartis Pharma AG, Basel, Switzerland
⨯
Nathan A. Stephens,

Affiliation Department of Clinical and Surgical Sciences, University of Edinburgh, Edinburgh, United Kingdom
⨯
Martin Degen,

Affiliation Novartis Institutes for BioMedical Research Basel, Novartis Pharma AG, Basel, Switzerland
⨯
Simone Degen,

Affiliation Novartis Institutes for BioMedical Research Basel, Novartis Pharma AG, Basel, Switzerland
⨯
Wilfried Frieauff,

Affiliation Novartis Institutes for BioMedical Research Basel, Novartis Pharma AG, Basel, Switzerland
⨯
Christian Lambert,

Affiliation Novartis Institutes for BioMedical Research Basel, Novartis Pharma AG, Basel, Switzerland
⨯
James A. Ross,

Affiliation Department of Clinical and Surgical Sciences, University of Edinburgh, Edinburgh, United Kingdom
⨯
Ronenn Roubenoff,

Affiliation Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, United States of America
⨯
David J. Glass,

Affiliation Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, United States of America
⨯
Carsten Jacobi ,

Contributed equally to this work with: Carsten Jacobi, Kenneth C. H. Fearon

Affiliation Novartis Institutes for BioMedical Research Basel, Novartis Pharma AG, Basel, Switzerland
⨯
Kenneth C. H. Fearon

Contributed equally to this work with: Carsten Jacobi, Kenneth C. H. Fearon

* E-mail: k.fearon@ed.ac.uk

Affiliation Department of Clinical and Surgical Sciences, University of Edinburgh, Edinburgh, United Kingdom
⨯

Clinical Classification of Cancer Cachexia: Phenotypic Correlates in Human Skeletal Muscle

Neil Johns,
Shinji Hatakeyama,
Nathan A. Stephens,
Martin Degen,
Simone Degen,
Wilfried Frieauff,
Christian Lambert,
James A. Ross,
Ronenn Roubenoff,
David J. Glass

Published: January 3, 2014
https://doi.org/10.1371/journal.pone.0083618

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