YopP-Expressing Variant of Y. pestis Activates a Potent Innate Immune Response Affording Cross-Protection against Yersiniosis and Tularemia

Ayelet Zauberman; Yehuda Flashner; Yinon Levy; Yaron Vagima; Avital Tidhar; Ofer Cohen; Erez Bar-Haim; David Gur; Moshe Aftalion; Gideon Halperin; Avigdor Shafferman; Emanuelle Mamroud

doi:10.1371/journal.pone.0083560

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Open Access

Peer-reviewed

Research Article

YopP-Expressing Variant of Y. pestis Activates a Potent Innate Immune Response Affording Cross-Protection against Yersiniosis and Tularemia

Ayelet Zauberman,

Affiliation Department of Biochemistry and Molecular Genetics, Israel Institute for Biological Research, Ness-Ziona, Israel
⨯
Yehuda Flashner,

Affiliation Department of Biochemistry and Molecular Genetics, Israel Institute for Biological Research, Ness-Ziona, Israel
⨯
Yinon Levy,

Affiliation Department of Biochemistry and Molecular Genetics, Israel Institute for Biological Research, Ness-Ziona, Israel
⨯
Yaron Vagima,

Affiliation Department of Biochemistry and Molecular Genetics, Israel Institute for Biological Research, Ness-Ziona, Israel
⨯
Avital Tidhar,

Affiliation Department of Biochemistry and Molecular Genetics, Israel Institute for Biological Research, Ness-Ziona, Israel
⨯
Ofer Cohen,

Affiliation Department of Biochemistry and Molecular Genetics, Israel Institute for Biological Research, Ness-Ziona, Israel
⨯
Erez Bar-Haim,

Affiliation Department of Biochemistry and Molecular Genetics, Israel Institute for Biological Research, Ness-Ziona, Israel
⨯
David Gur,

Affiliation Department of Biochemistry and Molecular Genetics, Israel Institute for Biological Research, Ness-Ziona, Israel
⨯
Moshe Aftalion,

Affiliation Department of Biochemistry and Molecular Genetics, Israel Institute for Biological Research, Ness-Ziona, Israel
⨯
Gideon Halperin,

Affiliation Department of Biochemistry and Molecular Genetics, Israel Institute for Biological Research, Ness-Ziona, Israel
⨯
Avigdor Shafferman,

Affiliation Department of Biochemistry and Molecular Genetics, Israel Institute for Biological Research, Ness-Ziona, Israel
⨯
Emanuelle Mamroud

* E-mail: emmym@iibr.gov.il

Affiliation Department of Biochemistry and Molecular Genetics, Israel Institute for Biological Research, Ness-Ziona, Israel
⨯

YopP-Expressing Variant of Y. pestis Activates a Potent Innate Immune Response Affording Cross-Protection against Yersiniosis and Tularemia

Ayelet Zauberman,
Yehuda Flashner,
Yinon Levy,
Yaron Vagima,
Avital Tidhar,
Ofer Cohen,
Erez Bar-Haim,
David Gur,
Moshe Aftalion,
Gideon Halperin

Published: December 16, 2013
https://doi.org/10.1371/journal.pone.0083560

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Francisella tularensis
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