Deletion of C9ORF72 Results in Motor Neuron Degeneration and Stress Sensitivity in C. elegans

Open Access

Peer-reviewed

Research Article

Martine Therrien,

Affiliations Centre de Recherche du Centre hospitalier de l'Université de Montréal (CRCHUM), Montréal, Québec, Canada, Département de Pathologie et Biologie Cellulaire, Université de Montréal, Montréal, Québec, Canada
⨯
Guy A. Rouleau,

Affiliation Montreal Neurological Institute, McGill University, Montréal, Québec, Canada
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Patrick A. Dion,

Affiliations Département de Pathologie et Biologie Cellulaire, Université de Montréal, Montréal, Québec, Canada, Montreal Neurological Institute, McGill University, Montréal, Québec, Canada
⨯
J. Alex Parker

* E-mail: ja.parker@umontreal.ca

Affiliations Centre de Recherche du Centre hospitalier de l'Université de Montréal (CRCHUM), Montréal, Québec, Canada, Département de Pathologie et Biologie Cellulaire, Université de Montréal, Montréal, Québec, Canada, Département de neuroscience, Université de Montréal, Montréal, Québec, Canada
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Motor neurons
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Osmotic shock
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RNA interference
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Amyotrophic lateral sclerosis
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Caenorhabditis elegans
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Phenotypes
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Toxicity
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Motor proteins
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