PTEN Increases Autophagy and Inhibits the Ubiquitin-Proteasome Pathway in Glioma Cells Independently of its Lipid Phosphatase Activity

Open Access

Peer-reviewed

Research Article

Rajaa Errafiy,

Affiliations Laboratorio de Biología Celular, Centro de Investigación Príncipe Felipe, Valencia, Spain, Laboratoire de Biochimie et Biologie Moléculaire, Faculté des Sciences, Ain chock, B.P 5366, Casablanca, Morocco
⨯
Carmen Aguado,

Affiliations Laboratorio de Biología Celular, Centro de Investigación Príncipe Felipe, Valencia, Spain, Centro de Investigación Biomédica en Red de Enfermedades, Raras Valencia, Spain
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Ghita Ghislat,

Affiliation Laboratorio de Biología Celular, Centro de Investigación Príncipe Felipe, Valencia, Spain
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Juan M. Esteve,

Affiliation Laboratorio de Biología Celular, Centro de Investigación Príncipe Felipe, Valencia, Spain
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Anabel Gil,

Affiliation Laboratorio de Biología Celular, Centro de Investigación Príncipe Felipe, Valencia, Spain
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Mohammed Loutfi,

Affiliation Laboratoire de Biochimie et Biologie Moléculaire, Faculté des Sciences, Ain chock, B.P 5366, Casablanca, Morocco
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Erwin Knecht

* E-mail: knecht@cipf.es

Affiliations Laboratorio de Biología Celular, Centro de Investigación Príncipe Felipe, Valencia, Spain, Centro de Investigación Biomédica en Red de Enfermedades, Raras Valencia, Spain
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Autophagic cell death
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Proteolysis
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Lipids
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Phosphatases
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Proteasomes
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Insulin
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Lysosomes
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Glioma cells
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