Polyoxygenated Cholesterol Ester Hydroperoxide Activates TLR4 and SYK Dependent Signaling in Macrophages

• Soo-Ho Choi,

  Affiliation Department of Medicine, University of California San Diego, La Jolla, California, United States of America

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• Huiyong Yin,

  Affiliations Key Laboratory of Food Safety Research, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China, Key Laboratory of Food Safety Risk Assessment, Ministry of Health, Beijing, China, School of Life Science and Technology, Shanghai Tech University, Shanghai, China

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• Amir Ravandi,

  Affiliation Institute of Cardiovascular Sciences, University of Manitoba, Winnipeg, Manitoba, Canada

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• Aaron Armando,

  Affiliations Department of Pharmacology, University of California San Diego, La Jolla, California, United States of America, Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, California, United States of America

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• Darren Dumlao,

  Affiliations Department of Pharmacology, University of California San Diego, La Jolla, California, United States of America, Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, California, United States of America

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• Jungsu Kim,

  Affiliation Department of Medicine, University of California San Diego, La Jolla, California, United States of America

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• Felicidad Almazan,

  Affiliation Department of Medicine, University of California San Diego, La Jolla, California, United States of America

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• Angela M. Taylor,

  Affiliation Cardiovascular Research Center, Department of Medicine, University of Virginia, Charlottesville, Virginia, United States of America

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• Coleen A. McNamara,

  Affiliation Cardiovascular Research Center, Department of Medicine, University of Virginia, Charlottesville, Virginia, United States of America

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• Sotirios Tsimikas,

  Affiliation Department of Medicine, University of California San Diego, La Jolla, California, United States of America

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• Edward A. Dennis,

  Affiliations Department of Pharmacology, University of California San Diego, La Jolla, California, United States of America, Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, California, United States of America

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• Joseph L. Witztum,

  Affiliation Department of Medicine, University of California San Diego, La Jolla, California, United States of America

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• Yury I. Miller

  * E-mail: yumiller@ucsd.edu

  Affiliation Department of Medicine, University of California San Diego, La Jolla, California, United States of America

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