Turnover of C99 is Controlled by a Crosstalk between ERAD and Ubiquitin-Independent Lysosomal Degradation in Human Neuroglioma Cells

Hianara A. Bustamante; Andrés Rivera-Dictter; Viviana A. Cavieres; Vanessa C. Muñoz; Alexis González; Yimo Lin; Gonzalo A. Mardones; Patricia V. Burgos

doi:10.1371/journal.pone.0083096

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Peer-reviewed

Research Article

Turnover of C99 is Controlled by a Crosstalk between ERAD and Ubiquitin-Independent Lysosomal Degradation in Human Neuroglioma Cells

Hianara A. Bustamante,

Affiliation Department of Physiology, School of Medicine and Centro de Investigación Sur-Austral en Enfermedades del Sistema Nervioso, Universidad Austral de Chile, Valdivia, Chile
⨯
Andrés Rivera-Dictter,

Affiliation Department of Physiology, School of Medicine and Centro de Investigación Sur-Austral en Enfermedades del Sistema Nervioso, Universidad Austral de Chile, Valdivia, Chile
⨯
Viviana A. Cavieres,

Affiliation Department of Physiology, School of Medicine and Centro de Investigación Sur-Austral en Enfermedades del Sistema Nervioso, Universidad Austral de Chile, Valdivia, Chile
⨯
Vanessa C. Muñoz,

Affiliation Department of Physiology, School of Medicine and Centro de Investigación Sur-Austral en Enfermedades del Sistema Nervioso, Universidad Austral de Chile, Valdivia, Chile
⨯
Alexis González,

Affiliation Department of Physiology, School of Medicine and Centro de Investigación Sur-Austral en Enfermedades del Sistema Nervioso, Universidad Austral de Chile, Valdivia, Chile
⨯
Yimo Lin,

Affiliation Department of Physiology, School of Medicine and Centro de Investigación Sur-Austral en Enfermedades del Sistema Nervioso, Universidad Austral de Chile, Valdivia, Chile
⨯
Gonzalo A. Mardones,

Affiliation Department of Physiology, School of Medicine and Centro de Investigación Sur-Austral en Enfermedades del Sistema Nervioso, Universidad Austral de Chile, Valdivia, Chile
⨯
Patricia V. Burgos

* E-mail: patricia.burgos@uach.cl

Affiliation Department of Physiology, School of Medicine and Centro de Investigación Sur-Austral en Enfermedades del Sistema Nervioso, Universidad Austral de Chile, Valdivia, Chile
⨯

Turnover of C99 is Controlled by a Crosstalk between ERAD and Ubiquitin-Independent Lysosomal Degradation in Human Neuroglioma Cells

Hianara A. Bustamante,
Andrés Rivera-Dictter,
Viviana A. Cavieres,
Vanessa C. Muñoz,
Alexis González,
Yimo Lin,
Gonzalo A. Mardones,
Patricia V. Burgos

Published: December 20, 2013
https://doi.org/10.1371/journal.pone.0083096

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Endoplasmic reticulum
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Ubiquitination
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