Crystal Structures and Molecular Dynamics Simulations of Thermophilic Malate Dehydrogenase Reveal Critical Loop Motion for Co-Substrate Binding

• Chih-Hung Hung ,

  Contributed equally to this work with: Chih-Hung Hung, Tzann-Shun Hwang, Yu-Yung Chang

  Affiliation Department of Agricultural Chemistry, National Taiwan University, Taipei, Taiwan

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• Tzann-Shun Hwang ,

  Contributed equally to this work with: Chih-Hung Hung, Tzann-Shun Hwang, Yu-Yung Chang

  Affiliation Graduate Institute of Biotechnology, Chinese Culture University, Taipei, Taiwan

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• Yu-Yung Chang ,

  Contributed equally to this work with: Chih-Hung Hung, Tzann-Shun Hwang, Yu-Yung Chang

  Affiliation Department of Agricultural Chemistry, National Taiwan University, Taipei, Taiwan

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• Huei-Ru Luo,

  Affiliation Graduate Institute of Biotechnology, Chinese Culture University, Taipei, Taiwan

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• Szu-Pei Wu,

  Affiliation Department of Biotechnology, Yuanpei University, Hsinchu, Taiwan

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• Chun-Hua Hsu

  * E-mail: andyhsu@ntu.edu.tw

  Affiliations Department of Agricultural Chemistry, National Taiwan University, Taipei, Taiwan, Genome and Systems Biology Degree Program; Center for Systems Biology, National Taiwan University, Taipei, Taiwan

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