HDAC Inhibitors Repress BARD1 Isoform Expression in Acute Myeloid Leukemia Cells via Activation of miR-19a and/or b

Ilaria Lepore; Carmela Dell’Aversana; Maxim Pilyugin; Mariarosaria Conte; Angela Nebbioso; Floriana De Bellis; Francesco P. Tambaro; Tiziana Izzo; Guillermo Garcia-Manero; Felicetto Ferrara; Irmgard Irminger-Finger; Lucia Altucci

doi:10.1371/journal.pone.0083018

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Peer-reviewed

Research Article

HDAC Inhibitors Repress BARD1 Isoform Expression in Acute Myeloid Leukemia Cells via Activation of miR-19a and/or b

Ilaria Lepore,

Affiliation Department of Biochemistry, Biophysics and General Pathology, Seconda Università degli Studi di Napoli, Naples, Italy
⨯
Carmela Dell’Aversana,

Affiliations Department of Biochemistry, Biophysics and General Pathology, Seconda Università degli Studi di Napoli, Naples, Italy, Institute of Genetics and Biophysics (IGB), Naples, Italy
⨯
Maxim Pilyugin,

Affiliation Molecular Gynecology and Obstetrics Laboratory, Department of Gynecology and Obstetrics and Department of Genetic and Laboratory Medicine, University Hospitals of Geneva, HUG, Genève, Switzerland
⨯
Mariarosaria Conte,

Affiliation Department of Biochemistry, Biophysics and General Pathology, Seconda Università degli Studi di Napoli, Naples, Italy
⨯
Angela Nebbioso,

Affiliation Department of Biochemistry, Biophysics and General Pathology, Seconda Università degli Studi di Napoli, Naples, Italy
⨯
Floriana De Bellis,

Affiliation Department of Biochemistry, Biophysics and General Pathology, Seconda Università degli Studi di Napoli, Naples, Italy
⨯
Francesco P. Tambaro,

Affiliations Department of Biochemistry, Biophysics and General Pathology, Seconda Università degli Studi di Napoli, Naples, Italy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
⨯
Tiziana Izzo,

Affiliation Division of Hematology and Stem Cell Transplantation Unit, Cardarelli Hospital, Naples, Italy
⨯
Guillermo Garcia-Manero,

Affiliation Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
⨯
Felicetto Ferrara,

Affiliation Division of Hematology and Stem Cell Transplantation Unit, Cardarelli Hospital, Naples, Italy
⨯
Irmgard Irminger-Finger,

Affiliation Molecular Gynecology and Obstetrics Laboratory, Department of Gynecology and Obstetrics and Department of Genetic and Laboratory Medicine, University Hospitals of Geneva, HUG, Genève, Switzerland
⨯
Lucia Altucci

* E-mail: lucia.altucci@unina2.it

Affiliations Department of Biochemistry, Biophysics and General Pathology, Seconda Università degli Studi di Napoli, Naples, Italy, Institute of Genetics and Biophysics (IGB), Naples, Italy
⨯

HDAC Inhibitors Repress BARD1 Isoform Expression in Acute Myeloid Leukemia Cells via Activation of miR-19a and/or b

Ilaria Lepore,
Carmela Dell’Aversana,
Maxim Pilyugin,
Mariarosaria Conte,
Angela Nebbioso,
Floriana De Bellis,
Francesco P. Tambaro,
Tiziana Izzo,
Guillermo Garcia-Manero,
Felicetto Ferrara

Published: December 11, 2013
https://doi.org/10.1371/journal.pone.0083018

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