ERK/PP1a/PLB/SERCA2a and JNK Pathways Are Involved in Luteolin-Mediated Protection of Rat Hearts and Cardiomyocytes following Ischemia/Reperfusion

Open Access

Peer-reviewed

Research Article

Xin Wu ,

Contributed equally to this work with: Xin Wu, Tongda Xu

Affiliation Institute of Cardiovascular Disease Research, Xuzhou Medical College, Xuzhou, Jiangsu, PR China
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Tongda Xu ,

Contributed equally to this work with: Xin Wu, Tongda Xu

Affiliation Department of The First Clinical College, Nanjing Traditional Chinese Medicine University, Nanjing, Jiangsu, PR China
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Dongye Li ,

* E-mail: ldy@xzmc.edu.cn (DL); sunh@xzmc.edu.cn (HS)

Affiliations Institute of Cardiovascular Disease Research, Xuzhou Medical College, Xuzhou, Jiangsu, PR China, Department of The First Clinical College, Nanjing Traditional Chinese Medicine University, Nanjing, Jiangsu, PR China
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Shasha Zhu,

Affiliation Institute of Cardiovascular Disease Research, Xuzhou Medical College, Xuzhou, Jiangsu, PR China
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Qiuping Chen,

Affiliation Institute of Cardiovascular Disease Research, Xuzhou Medical College, Xuzhou, Jiangsu, PR China
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Wenjing Hu,

Affiliation Institute of Cardiovascular Disease Research, Xuzhou Medical College, Xuzhou, Jiangsu, PR China
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Defeng Pan,

Affiliation Institute of Cardiovascular Disease Research, Xuzhou Medical College, Xuzhou, Jiangsu, PR China
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Hong Zhu,

Affiliation Institute of Cardiovascular Disease Research, Xuzhou Medical College, Xuzhou, Jiangsu, PR China
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Hong Sun

* E-mail: ldy@xzmc.edu.cn (DL); sunh@xzmc.edu.cn (HS)

Affiliation Department of Physiology, Xuzhou Medical College, Xuzhou, Jiangsu, PR China
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Cardiomyocytes
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Apoptosis
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Heart
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Muscle cells
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Reperfusion
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c-Jun N-terminal kinase signaling cascade
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Ischemia
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Phosphorylation
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