NFBD1/MDC1 Is Phosphorylated by PLK1 and Controls G2/M Transition through the Regulation of a TOPOIIα-Mediated Decatenation Checkpoint

Open Access

Peer-reviewed

Research Article

Kiyohiro Ando,

Affiliations Division of Biochemistry and Innovative Cancer Therapeutics, Chiba Cancer Center Research Institute, Chiba, Japan, Division of Clinical Oncology Research, Shonan Kamakura General Hospital, Kanagawa, Japan
⨯
Toshinori Ozaki,

Affiliation Laboratory of Anti-tumor Research, Chiba Cancer Center Research Institute, Chiba, Japan
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Toru Hirota,

Affiliation Department of Experimental Pathology, Cancer Institute of the Japanese Foundation for Cancer Research (JFCR), Tokyo, Japan
⨯
Akira Nakagawara

* E-mail: akiranak@chiba-cc.jp

Affiliation Division of Biochemistry and Innovative Cancer Therapeutics, Chiba Cancer Center Research Institute, Chiba, Japan
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Phosphorylation
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Transfection
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HeLa cells
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Immunoprecipitation
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Small interfering RNA
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DNA damage
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G2 phase
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Immunoblotting
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