Structural Characterization of a Therapeutic Anti-Methamphetamine Antibody Fragment: Oligomerization and Binding of Active Metabolites

Open Access

Peer-reviewed

Research Article

Eric C. Peterson ,

Contributed equally to this work with: Eric C. Peterson, Reha Celikel

Affiliation Department of Pharmacology and Toxicology, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States of America
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Reha Celikel ,

Contributed equally to this work with: Eric C. Peterson, Reha Celikel

Affiliation Department of Physiology and Biophysics, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States of America
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Kuppan Gokulan,

Affiliation Department of Physiology and Biophysics, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States of America
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Kottayil I. Varughese

* E-mail: KIVarughese@uams.edu

Affiliation Department of Physiology and Biophysics, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States of America
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Crystal structure
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Antibodies
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Drug interactions
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Electron density
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Hydrogen bonding
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Histidine
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Molecular structure
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Sulfates
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