Human L-ficolin, a Recognition Molecule of the Lectin Activation Pathway of Complement, Activates Complement by Binding to Pneumolysin, the Major Toxin of Streptococcus pneumoniae

• Youssif M. Ali,

  Affiliations Department of Infection, Immunity and Inflammation, University of Leicester, Leicester, United Kingdom, Department of Microbiology, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt

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• Hany I. Kenawy,

  Affiliations Department of Infection, Immunity and Inflammation, University of Leicester, Leicester, United Kingdom, Department of Microbiology, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt

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• Adnan Muhammad,

  Affiliation Department of Infection, Immunity and Inflammation, University of Leicester, Leicester, United Kingdom

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• Robert B. Sim,

  Affiliation Department of Infection, Immunity and Inflammation, University of Leicester, Leicester, United Kingdom

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• Peter W. Andrew ,

  Contributed equally to this work with: Peter W. Andrew, Wilhelm J. Schwaeble

  Affiliation Department of Infection, Immunity and Inflammation, University of Leicester, Leicester, United Kingdom

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• Wilhelm J. Schwaeble

  Contributed equally to this work with: Peter W. Andrew, Wilhelm J. Schwaeble

  * E-mail: ws5@le.ac.uk

  Affiliation Department of Infection, Immunity and Inflammation, University of Leicester, Leicester, United Kingdom

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