Histology Verification Demonstrates That Biospectroscopy Analysis of Cervical Cytology Identifies Underlying Disease More Accurately than Conventional Screening: Removing the Confounder of Discordance

Ketan Gajjar; Abdullah A. Ahmadzai; George Valasoulis; Júlio Trevisan; Christina Founta; Maria Nasioutziki; Aristotelis Loufopoulos; Maria Kyrgiou; Sofia Melina Stasinou; Petros Karakitsos; Evangelos Paraskevaidis; Bianca Da Gama-Rose; Pierre L. Martin-Hirsch; Francis L. Martin

doi:10.1371/journal.pone.0082416

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Peer-reviewed

Research Article

Histology Verification Demonstrates That Biospectroscopy Analysis of Cervical Cytology Identifies Underlying Disease More Accurately than Conventional Screening: Removing the Confounder of Discordance

Ketan Gajjar ,

* E-mail: gajjarkb@gmail.com (KG); f.martin@lancaster.ac.uk (FLM)

Affiliations Centre for Biophotonics, Lancaster Environment Centre, Lancaster University, Lancaster, United Kingdom, Department of Obstetrics and Gynaecology, Lancashire Teaching Hospitals NHS Foundation Trust, Preston, United Kingdom
⨯
Abdullah A. Ahmadzai,

Affiliation Centre for Biophotonics, Lancaster Environment Centre, Lancaster University, Lancaster, United Kingdom
⨯
George Valasoulis,

Affiliation Department of Obstetrics and Gynaecology, University Hospital of Ioannina, Ioannina, Greece
⨯
Júlio Trevisan,

Affiliation Centre for Biophotonics, Lancaster Environment Centre, Lancaster University, Lancaster, United Kingdom
⨯
Christina Founta,

Affiliations Department of Obstetrics and Gynaecology, Lancashire Teaching Hospitals NHS Foundation Trust, Preston, United Kingdom, Department of Obstetrics and Gynaecology, University Hospital of Ioannina, Ioannina, Greece
⨯
Maria Nasioutziki,

Affiliation Second Department of Obstetrics and Gynaecology, Aristotle University of Thessaloniki - Hippokration Hospital Thessaloniki, Thessaloniki, Greece
⨯
Aristotelis Loufopoulos,

Affiliation Second Department of Obstetrics and Gynaecology, Aristotle University of Thessaloniki - Hippokration Hospital Thessaloniki, Thessaloniki, Greece
⨯
Maria Kyrgiou,

Affiliations Queen Charlotte’s & Chelsea - Hammersmith Hospital, Imperial Healthcare NHS Trust, London, United Kingdom, Department of Surgery and Cancer, Imperial College, London, United Kingdom
⨯
Sofia Melina Stasinou,

Affiliations Department of Obstetrics and Gynaecology, University Hospital of Ioannina, Ioannina, Greece, Queen Charlotte’s & Chelsea - Hammersmith Hospital, Imperial Healthcare NHS Trust, London, United Kingdom
⨯
Petros Karakitsos,

Affiliation Department of Cytopathology, “Attikon” Hospital, University of Athens, Athens, Greece
⨯
Evangelos Paraskevaidis,

Affiliation Department of Obstetrics and Gynaecology, University Hospital of Ioannina, Ioannina, Greece
⨯
Bianca Da Gama-Rose,

Affiliation Department of Obstetrics and Gynaecology, Lancashire Teaching Hospitals NHS Foundation Trust, Preston, United Kingdom
⨯
Pierre L. Martin-Hirsch,

Affiliation Department of Obstetrics and Gynaecology, Lancashire Teaching Hospitals NHS Foundation Trust, Preston, United Kingdom
⨯
Francis L. Martin

* E-mail: gajjarkb@gmail.com (KG); f.martin@lancaster.ac.uk (FLM)

Affiliation Centre for Biophotonics, Lancaster Environment Centre, Lancaster University, Lancaster, United Kingdom
⨯

Histology Verification Demonstrates That Biospectroscopy Analysis of Cervical Cytology Identifies Underlying Disease More Accurately than Conventional Screening: Removing the Confounder of Discordance

Ketan Gajjar,
Abdullah A. Ahmadzai,
George Valasoulis,
Júlio Trevisan,
Christina Founta,
Maria Nasioutziki,
Aristotelis Loufopoulos,
Maria Kyrgiou,
Sofia Melina Stasinou,
Petros Karakitsos

Published: January 3, 2014
https://doi.org/10.1371/journal.pone.0082416

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Cytology
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Histology
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Infrared spectroscopy
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