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Open Access
Peer-reviewed
Research Article
Attenuation of Hyperlipidemia- and Diabetes-Induced Early-Stage Apoptosis and Late-Stage Renal Dysfunction via Administration of Fibroblast Growth Factor-21 Is Associated with Suppression of Renal Inflammation
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Chi Zhang,
Affiliations Chinese-American Research Institute for Diabetic Complications, Wenzhou Medical University, Wenzhou, Zhejiang, China, Ruian Center of the Chinese-American Research Institute for Diabetic Complications, Third Affiliated Hospital of the Wenzhou Medical University, Wenzhou, Zhejiang, China
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Minglong Shao,
Affiliations Chinese-American Research Institute for Diabetic Complications, Wenzhou Medical University, Wenzhou, Zhejiang, China, Ruian Center of the Chinese-American Research Institute for Diabetic Complications, Third Affiliated Hospital of the Wenzhou Medical University, Wenzhou, Zhejiang, China, School of Pharmacy, Wenzhou Medical University, Wenzhou, Zhejiang, China
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Hong Yang,
Affiliation Ruian Center of the Chinese-American Research Institute for Diabetic Complications, Third Affiliated Hospital of the Wenzhou Medical University, Wenzhou, Zhejiang, China
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Liangmiao Chen,
Affiliation Ruian Center of the Chinese-American Research Institute for Diabetic Complications, Third Affiliated Hospital of the Wenzhou Medical University, Wenzhou, Zhejiang, China
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Lechu Yu,
Affiliations Chinese-American Research Institute for Diabetic Complications, Wenzhou Medical University, Wenzhou, Zhejiang, China, Ruian Center of the Chinese-American Research Institute for Diabetic Complications, Third Affiliated Hospital of the Wenzhou Medical University, Wenzhou, Zhejiang, China
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Weitao Cong,
Affiliations Chinese-American Research Institute for Diabetic Complications, Wenzhou Medical University, Wenzhou, Zhejiang, China, School of Pharmacy, Wenzhou Medical University, Wenzhou, Zhejiang, China
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Haishan Tian,
Affiliation School of Pharmacy, Wenzhou Medical University, Wenzhou, Zhejiang, China
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Fangfang Zhang,
Affiliations Chinese-American Research Institute for Diabetic Complications, Wenzhou Medical University, Wenzhou, Zhejiang, China, Ruian Center of the Chinese-American Research Institute for Diabetic Complications, Third Affiliated Hospital of the Wenzhou Medical University, Wenzhou, Zhejiang, China
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Peng Cheng,
Affiliations Chinese-American Research Institute for Diabetic Complications, Wenzhou Medical University, Wenzhou, Zhejiang, China, Ruian Center of the Chinese-American Research Institute for Diabetic Complications, Third Affiliated Hospital of the Wenzhou Medical University, Wenzhou, Zhejiang, China
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Litai Jin,
Affiliations Chinese-American Research Institute for Diabetic Complications, Wenzhou Medical University, Wenzhou, Zhejiang, China, School of Pharmacy, Wenzhou Medical University, Wenzhou, Zhejiang, China
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Yi Tan,
Affiliations Chinese-American Research Institute for Diabetic Complications, Wenzhou Medical University, Wenzhou, Zhejiang, China, Ruian Center of the Chinese-American Research Institute for Diabetic Complications, Third Affiliated Hospital of the Wenzhou Medical University, Wenzhou, Zhejiang, China, Kosair Children’s Hospital Research Institute at the Department of Pediatrics, University of Louisville, Louisville, Kentucky, United States of America
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Xiaokun Li,
Affiliations Chinese-American Research Institute for Diabetic Complications, Wenzhou Medical University, Wenzhou, Zhejiang, China, School of Pharmacy, Wenzhou Medical University, Wenzhou, Zhejiang, China
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Lu Cai ,
* E-mail: lu89118@medmail.com.cn (X. Lu); lu.cai@louisville.edu (L. Cai)
Affiliations Chinese-American Research Institute for Diabetic Complications, Wenzhou Medical University, Wenzhou, Zhejiang, China, Ruian Center of the Chinese-American Research Institute for Diabetic Complications, Third Affiliated Hospital of the Wenzhou Medical University, Wenzhou, Zhejiang, China, Kosair Children’s Hospital Research Institute at the Department of Pediatrics, University of Louisville, Louisville, Kentucky, United States of America
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Xuemian Lu
* E-mail: lu89118@medmail.com.cn (X. Lu); lu.cai@louisville.edu (L. Cai)
Affiliations Chinese-American Research Institute for Diabetic Complications, Wenzhou Medical University, Wenzhou, Zhejiang, China, Ruian Center of the Chinese-American Research Institute for Diabetic Complications, Third Affiliated Hospital of the Wenzhou Medical University, Wenzhou, Zhejiang, China
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Attenuation of Hyperlipidemia- and Diabetes-Induced Early-Stage Apoptosis and Late-Stage Renal Dysfunction via Administration of Fibroblast Growth Factor-21 Is Associated with Suppression of Renal Inflammation
- Chi Zhang,
- Minglong Shao,
- Hong Yang,
- Liangmiao Chen,
- Lechu Yu,
- Weitao Cong,
- Haishan Tian,
- Fangfang Zhang,
- Peng Cheng,
- Litai Jin
- Published: December 9, 2013
- https://doi.org/10.1371/journal.pone.0082275