TGF-ß Regulates Enamel Mineralization and Maturation through KLK4 Expression

Andrew Cho; Naoto Haruyama; Bradford Hall; Mary Jo S. Danton; Lu Zhang; Praveen Arany; David J. Mooney; Yassine Harichane; Michel Goldberg; Carolyn W. Gibson; Ashok B. Kulkarni

doi:10.1371/journal.pone.0082267

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Open Access

Peer-reviewed

Research Article

TGF-ß Regulates Enamel Mineralization and Maturation through KLK4 Expression

Andrew Cho,

Affiliation Gene Transfer Core, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Naoto Haruyama,

Affiliations Functional Genomics Section, Laboratory of Cell and Developmental Biology, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, United States of America, Global Center of Excellence (GCOE) Program, International Research Center for Molecular Science in Tooth and Bone Disease, Tokyo Medical and Dental University, Tokyo, Japan
⨯
Bradford Hall,

Affiliation Functional Genomics Section, Laboratory of Cell and Developmental Biology, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Mary Jo S. Danton,

Affiliation Functional Genomics Section, Laboratory of Cell and Developmental Biology, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Lu Zhang,

Affiliation Functional Genomics Section, Laboratory of Cell and Developmental Biology, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Praveen Arany,

Affiliation Harvard University, Cambridge, Massachusetts, United States of America
⨯
David J. Mooney,

Affiliation Harvard University, Cambridge, Massachusetts, United States of America
⨯
Yassine Harichane,

Affiliation Université Paris Descartes, Paris, France
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Michel Goldberg,

Affiliation Université Paris Descartes, Paris, France
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Carolyn W. Gibson,

Affiliation University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Ashok B. Kulkarni

* E-mail: ak40m@nih.gov

Affiliations Gene Transfer Core, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, United States of America, Functional Genomics Section, Laboratory of Cell and Developmental Biology, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, United States of America
⨯

TGF-ß Regulates Enamel Mineralization and Maturation through KLK4 Expression

Andrew Cho,
Naoto Haruyama,
Bradford Hall,
Mary Jo S. Danton,
Lu Zhang,
Praveen Arany,
David J. Mooney,
Yassine Harichane,
Michel Goldberg,
Carolyn W. Gibson

Published: November 20, 2013
https://doi.org/10.1371/journal.pone.0082267

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Ameloblasts
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Molars
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Teeth
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Extracellular matrix proteins
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